Continuum Model of Light Response in the Retina

被引:0
作者
Yin, Shijie [1 ]
Lovell, Nigel H. [1 ]
Suaning, Gregg J. [1 ]
Dokos, Socrates [1 ]
机构
[1] Univ New S Wales, Grad Sch Biomed Engn, Sydney, NSW 2052, Australia
来源
2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | 2011年
关键词
GANGLION-CELLS; ELECTRICAL-STIMULATION; BIPOLAR CELLS;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A continuum model is presented of the retinal ON cone pathway to simulate the effects of light stimulation, motivated to provide validation of retinal response to electrical stimulation from vision implants. The model embodies four cell types involved in the direct pathway of light from cones to retinal ganglion cells. Center and surround mechanisms were incorporated through lateral inhibition via horizontal cells and convergence of inputs at the level of bipolar cells. Simulations were performed to investigate the network response to large and small spots of light. The results indicate the presence of surround suppression is correlated to spot size, consistent with experimental findings.
引用
收藏
页码:908 / 911
页数:4
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