One of the challenges of managing patients with antiphospholipid syndrome is the prevention of rethrombosis (secondary prophylaxis). Risk stratification, i.e. traditional cardiovascular and thrombosis risk factors, systemic autoimmune diseases, antiphospholipid antibody profile, and the intensity of anticoagulation are all relevant to the management of APS patients with recurrent thrombosis. The paper will review "state of the art" strategies for optimizing therapy for APS patients with recurrent thrombosis.
机构:Univ N Carolina, Div Rheumatol Allergy & Immunol, Dept Med, Chapel Hill, NC 27599 USA
Farmer-Boatwright, Mary Katherine
Roubey, Robert A. S.
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Univ N Carolina, Div Rheumatol Allergy & Immunol, Dept Med, Chapel Hill, NC 27599 USAUniv N Carolina, Div Rheumatol Allergy & Immunol, Dept Med, Chapel Hill, NC 27599 USA
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McMaster Univ, 1280 Main St West, Hamilton, ON L8S 4L8, CanadaMcMaster Univ, 1280 Main St West, Hamilton, ON L8S 4L8, Canada
Legault, Kimberly Janet
Ugarte, Amaia
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Univ Basque Country, Autoimmune Dis Res Unit, Dept Internal Med, BioCruces Hlth Res Inst,Hosp Univ Cruces, Bizkaia, The Basque Coun, SpainMcMaster Univ, 1280 Main St West, Hamilton, ON L8S 4L8, Canada
Ugarte, Amaia
Crowther, Mark Andrew
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McMaster Univ, 1280 Main St West, Hamilton, ON L8S 4L8, CanadaMcMaster Univ, 1280 Main St West, Hamilton, ON L8S 4L8, Canada
Crowther, Mark Andrew
Ruiz-Irastorza, Guillermo
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Univ Basque Country, Autoimmune Dis Res Unit, Dept Internal Med, BioCruces Hlth Res Inst,Hosp Univ Cruces, Bizkaia, The Basque Coun, SpainMcMaster Univ, 1280 Main St West, Hamilton, ON L8S 4L8, Canada