Determination of nicarbazin in feeds using liquid chromatography-electrospray mass spectrometry

被引：22
|
作者：
Cannavan, A [1 ]
Ball, G [1 ]
Kennedy, DG [1 ]
机构：
[1] Dept Agr No Ireland, Vet Sci Div, Belfast BT4 3SD, Antrim, North Ireland
来源：
ANALYST | 1999年 / 124卷 / 10期
基金：
英国惠康基金;
关键词：
D O I：
10.1039/a904557k
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A method is presented for the determination of the 4,4'-dinitrocarbanilide component of the coccidiostat nicarbazin in animal feeds. Samples are extracted by shaking with methanol and analysed, without further clean-up, using liquid chromatography-electrospray mass spectrometry. A deuterated form of the analyte is employed as internal standard to improve the repeatability of the method. The method has been validated at levels between 0.1 and 100 mg kg(-1) with internal standard corrected recoveries between 88 and 101% and RSD values < 8%.
引用
收藏
页码：1431 / 1434
页数：4
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