IMMUNOLOGY The chronicles of T-cell exhaustion

被引:27
作者
Amezquita, Robert A. [1 ]
Kaech, Susan M. [1 ]
机构
[1] Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
关键词
D O I
10.1038/nature21508
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
T cells of the immune system often fail to target cancer cells because they enter a dysfunctional state known as exhaustion. Molecular analysis of T-cell exhaustion provides insights into the clinical use of these cells.
引用
收藏
页码:190 / 191
页数:3
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