Multi-channel deep tissue flowmetry based on temporal diffuse speckle contrast analysis

被引：50

作者：

Bi, Renzhe ^{[1
]}

Dong, Jing ^{[1
]}

Lee, Kijoon ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637457, Singapore

来源：

OPTICS EXPRESS | 2013年 / 21卷 / 19期

关键词：

CEREBRAL-BLOOD-FLOW; LOW-FREQUENCY OSCILLATIONS; CORRELATION SPECTROSCOPY; HEMODYNAMICS; VALIDATION; DYNAMICS; INFANTS; TIME;

D O I：

10.1364/OE.21.022854

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Recently, diffuse speckle contrast analysis (DSCA) was introduced as a competent modality for deep tissue blood flow measurement, where the speckle contrast is calculated over spatial domain on the CCD image of diffuse reflectance. In this paper, we introduce time-domain DSCA where temporal statistics are used for speckle contrast calculation and results in the same deep tissue flow measurement. This new modality is especially suitable for multi-channel real-time flowmetry, and we demonstrate its performance on human arm during cuff occlusion test. Independent component analysis (ICA) study on multi-channel data shows promising results about underlying physiology. (c) 2013 Optical Society of America

引用

页码：22854 / 22861

页数：8

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