Dose-volume population histogram: a new tool for evaluating plans whilst considering geometrical uncertainties

被引：10
|
作者：
Nguyen, T. B. [1 ,2 ]
Hoole, A. C. F. [1 ]
Burnet, N. G. [2 ]
Thomas, S. J. [1 ]
机构：
[1] Addenbrookes Hosp, Dept Med Phys, Cambridge CB2 0QQ, England
[2] Univ Cambridge, Addenbrookes Hosp, Ctr Oncol, Dept Oncol, Cambridge CB2 0QQ, England
来源：
PHYSICS IN MEDICINE AND BIOLOGY | 2009年 / 54卷 / 04期
关键词：
RADIATION-THERAPY; SPINAL-CORD; CONVOLUTION METHOD; ORGAN MOTION; RADIOTHERAPY; RISK; DISTRIBUTIONS; PROBABILITY; LIMITATIONS; SIMULATION;
D O I：
10.1088/0031-9155/54/4/008
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We present a method to incorporate geometrical uncertainties into dose-volume histogram evaluation: the dose-volume population histogram (DVPH). For each dose-volume point, the probability of the plan DVH meeting the constraint is calculated. The use of DVPH for the target shows that the minimum dose to the PTV might not be representative of the minimum dose to the CTV considering geometrical uncertainties when the PTV extends into the buildup region. For OARs, the DVH obtained from DVPH with 90% confidence level is found to be different to the planning organ at risk volume (PRV) DVH recommended by ICRU 62, especially for parallel organs.
引用
收藏
页码：935 / 947
页数：13
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