Biosynthesis and Catabolism of Purine Alkaloids

被引：26

作者：

Ashihara, Hiroshi ^{[1
]}

Yokota, Takao ^{[2
]}

Crozier, Alan ^{[3
]}

机构：

[1] Ochanomizu Univ, Dept Biol Sci, Bunkyo Ku, Tokyo 112, Japan

[2] Teikyo Univ, Dept Biosci, Utsunomiya, Tochigi, Japan

[3] Univ Glasgow, Sch Med, Coll Med Vet & Life Sci, Glasgow, Lanark, Scotland

来源：

NEW LIGHT ON ALKALOID BIOSYNTHESIS AND FUTURE PROSPECTS | 2013年 / 68卷

关键词：

TEA CAMELLIA-SINENSIS; CAFFEINE BIOSYNTHESIS; COFFEA-ARABICA; THEOBROMA-CACAO; N-METHYLTRANSFERASES; TOBACCO PLANTS; ADENINE METABOLISM; DIFFERENT PARTS; DE-NOVO; LEAVES;

D O I：

10.1016/B978-0-12-408061-4.00004-3

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A limited number of plant species accumulate purine alkaloids, such as caffeine and theobromine, which are synthesized from xanthosine, a catabolite of purine nucleotides. The main biosynthetic pathway is a sequence consisting of xanthosine -> 7-methylxanthosine -> 7-methylxanthine -> theobromine -> caffeine. This review summarizes the occurrence of purine alkaloids in the plant kingdom, the caffeine biosynthesis routes from purine precursors, the enzymes and genes of N-methyltransferases, key enzymes of caffeine biosynthesis, caffeine catabolism and the possible ecological role of caffeine. Finally, we introduce transgenic plants in which caffeine production is either suppressed or induced by the introduction of caffeine encoded genes. Such plants have the potential to be used for the production of decaffeinated coffee and tea or as natural pesticides in agriculturally important crops.

引用

页码：111 / 138

页数：28

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