5(4H)-oxazolones: Synthesis and biological activities

被引：18
作者：
Haneen, David S. A. [1 ]
Abou-Elmagd, Wael S. I. [1 ]
Youssef, Ahmed S. A. [1 ]
机构：
[1] Ain Shams Univ, Chem Dept, Fac Sci, Cairo, Egypt
来源：
SYNTHETIC COMMUNICATIONS | 2021年 / 51卷 / 02期
关键词：
5(4H)-Oxazolones; biological evaluation; azlactones; erlenmeyer synthesis; CHLORIDE CATALYZED SYNTHESIS; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; OXAZOLONE DERIVATIVES; ACID; RING; 4-BENZYLIDENE-2-METHYL-5-OXAZOLONE; METHODOLOGY; INHIBITORS; MECHANISM;
D O I：
10.1080/00397911.2020.1825746
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In this review, we summarize all the synthetic methods and a variety of different techniques which has been used to prepare 4-arylidene-2-subsititued-5(4H)-oxazolone derivatives followed by a focused survey on the biological importance of this nucleus.
引用
收藏
页码：215 / 233
页数：19
相关论文
共 86 条
[1]  
Abdel-Aty S. A., 2009, WORLD J AGR SCI, V5
[2]  
ADAMS R, 1946, ORG REACTIONS, V3, P198
[3]  
Akram W. A. M., 2014, IJPRS, V3
[4]   Synthesis of 4-benzylidene-oxazol-5(4H)-imines, structural analogs of PK11195, under Bischler-Napieralski conditions [J].
Almaraz-Giron, Marco A. ;
Vazquez, Alfredo .
TETRAHEDRON LETTERS, 2017, 58 (08) :785-788
[5]   Microwave Assisted Improved Method for the Synthesis of Pyrazole Containing 2,4,-Disubstituted Oxazole-5-one and their Antimicrobial Activity [J].
Argade, N. D. ;
Kalrale, B. K. ;
Gill, C. H. .
E-JOURNAL OF CHEMISTRY, 2008, 5 (01) :120-129
[6]   Synthesis and antitumor activity evaluation of some novel pyrazolotriazine derivatives [J].
Atta-Allah, Saad R. ;
Gouhar, Rasha S. ;
Hemdan, Magdy M. ;
Abou-Elmagd, Wael S. I. ;
Haneen, David S. A. ;
Kandeel, Kamal A. A. ;
Youssef, Ahmed S. A. .
SYNTHETIC COMMUNICATIONS, 2017, 47 (04) :299-309
[7]   Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection [J].
Bala, Shashi ;
Tilahun, Yaphet ;
Taha, Odette ;
Alao, Hawau ;
Kodys, Karen ;
Catalano, Donna ;
Szabo, Gyongyi .
JOURNAL OF TRANSLATIONAL MEDICINE, 2012, 10
[8]   SYNTHESIS OF 2-METHYL-(Z)-4-(PHENYLIMINO)NAPHTH[2,3-D]OXAZOL-9-ONE, A MONOIMINE QUINONE WITH SELECTIVE CYTOTOXICITY TOWARD CANCER-CELLS [J].
BENEDETTIDOCTOROVICH, V ;
BURGESS, EM ;
LAMBROPOULOS, J ;
LEDNICER, D ;
VANDERVEER, D ;
ZALKOW, LH .
JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (05) :710-712
[9]  
Bergmann M, 1926, LIEBIGS ANN CHEM, V448, P20
[10]   Reaction of 4-benzylidene-2-methyl-5-oxazolone with amines, Part 2: Influence of substituents in para-position in the phenyl ring and a substituent on amine nitrogen atom on the reaction kinetics [J].
Betlakowska, B ;
Banecki, B ;
Czaplewski, C ;
Lankiewicz, L ;
Wiczk, W .
INTERNATIONAL JOURNAL OF CHEMICAL KINETICS, 2002, 34 (03) :148-155
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