Water-Soluble and pH-Responsive Polymeric Nanotubes from Cyclic Peptide Templates

被引：44

作者：

Chapman, Robert ^{[1
]}

Warr, Gregory G. ^{[1
]}

Perrier, Sebastien ^{[1
]}

Jolliffe, Katrina A. ^{[1
]}

机构：

[1] Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 06期

基金：

澳大利亚研究理事会;

关键词：

nanotubes; peptides; polymers; self-assembly; LIVING RADICAL POLYMERIZATION; ASSEMBLING ORGANIC NANOTUBES; FRAGMENTATION CHAIN TRANSFER; ANGLE NEUTRON-SCATTERING; RAFT PROCESS; NONIONIC SURFACTANTS; DESIGN; UPDATE;

D O I：

10.1002/chem.201203602

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Water-soluble organic nanotubes were prepared by convergently conjugating polymers of hydroxyethyl acrylate (HEA) and acrylic acid (AA) to self-assembling cyclic octapeptides of alternating D and Lchirality. The structure of the self-assembled tubes was characterised in a number of polar solvents, and notably water, by using light scattering, TEM and small angle neutron scattering (SANS) techniques. In addition, the self-assembly into tubes could be controlled by exploiting the pH responsiveness of acrylic acid polymers.

引用

页码：1955 / 1961

页数：7

共 29 条

[1]

Bong D.T., 2001, Angew. Chem, V113, P1016

[2]

Bong DT, 2001, ANGEW CHEM INT EDIT, V40, P988, DOI 10.1002/1521-3773(20010316)40:6<988::AID-ANIE9880>3.3.CO

[3]

2-E

[4] Towards functional bionanomaterials based on self-assembling cyclic peptide nanotubes [J].