Cancer-Associated Venous Thromboembolic Disease, Version 1.2015 Featured Updates to the NCCN Guidelines

被引：103

作者：

Streiff, Michael B. ^{[1
]}

Holmstrom, Bjorn ^{[2
]}

Ashrani, Aneel ^{[3
]}

Bockenstedt, Paula L. ^{[4
]}

Chesney, Carolyn ^{[5
]}

Eby, Charles ^{[6
,7
]}

Fanikos, John ^{[8
]}

Fenninger, Randolph B. ^{[9
]}

Fogerty, Annemarie E. ^{[10
]}

Gao, Shuwei ^{[11
]}

Goldhaber, Samuel Z. ^{[8
]}

Hendrie, Paul ^{[12
]}

Kuderer, Nicole ^{[12
]}

Lee, Alfred ^{[13
]}

Lee, Jason T. ^{[14
]}

Lovrincevic, Mirjana ^{[15
]}

Millenson, Michael M. ^{[16
]}

Neff, Anne T. ^{[17
]}

Ortel, Thomas L. ^{[18
]}

Paschal, Rita ^{[19
]}

Shattil, Sanford ^{[20
]}

Siddiqi, Tanya ^{[21
]}

Smock, Kristi J. ^{[22
]}

Soff, Gerald ^{[23
]}

Wang, Tzu-Fei ^{[24
,25
]}

Yee, Gary C. ^{[26
]}

Zakarija, Anaadriana ^{[27
]}

McMillian, Nicole ^{[28
]}

Engh, Anita M. ^{[28
]}

机构：

[1] Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD USA

[2] Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33682 USA

[3] Mayo Clin, Ctr Canc, Rochester, MN USA

[4] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[5] Univ Tennessee, St Jude Childrens Res Hosp, Hlth Sci Ctr, Knoxville, TN 37996 USA

[6] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA

[7] Washington Univ, Sch Med, St Louis, MO 63130 USA

[8] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[9] Natl Blood Clot Alliance, Strockville, MD USA

[10] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA

[11] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[12] Univ Washington, Seattle Canc Care Alliance, Seattle, WA 98195 USA

[13] Smilow Canc Hosp, Yale Canc Ctr, New Haven, CT USA

[14] Stanford Canc Inst, Stanford, CA USA

[15] Roswell Pk Canc Inst, Buffalo, NY USA

[16] Fox Chase Canc Ctr, Philadelphia, PA USA

[17] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[18] Duke Canc Inst, Durham, NC USA

[19] Univ Alabama, Birmingham Comprehens Canc Ctr, Tuscaloosa, AL 35487 USA

[20] UC San Diego Moores Canc Ctr, San Diego, CA USA

[21] City Hope Comprehens Canc Ctr, Duarte, CA USA

[22] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[23] Mem Sloan Kettering Canc Ctr, New York, NY USA

[24] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Columbus, OH 43210 USA

[25] Ohio State Univ, Solove Res Inst, Columbus, OH 43210 USA

[26] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA

[27] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[28] Natl Comprehens Canc Network, Washington, DC USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2015年 / 13卷 / 09期

关键词：

BODY-MASS INDEX; CHRONIC KIDNEY-DISEASE; MOLECULAR-WEIGHT HEPARIN; DEEP-VEIN THROMBOSIS; Y GASTRIC BYPASS; MORBIDLY OBESE-PATIENTS; BARIATRIC SURGERY; RISK-FACTORS; PULMONARY-EMBOLISM; POSTOPERATIVE FONDAPARINUX;

D O I：

10.6004/jnccn.2015.0133

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The NCCN Guidelines for Cancer-Associated Venous Thromboembolic Disease outline strategies for treatment and prevention of venous thromboembolism (VTE) in adult patients with a diagnosis of cancer or for whom cancer is clinically suspected. VTE is a common complication in patients with cancer, which places them at greater risk for morbidity and mortality. Therefore, risk-appropriate prophylaxis is an essential component for the optimal care of inpatients and outpatients with cancer. Critical to meeting this goal is ensuring that patients get the most effective medication in the correct dose. Body weight has a significant impact on blood volume and drug clearance. Because obesity is a common health problem in industrialized societies, cancer care providers are increasingly likely to treat obese patients in their practice. Obesity is a risk factor common to VTE and many cancers, and may also impact the anticoagulant dose needed for safe and effective prophylaxis. These NCCN Guidelines Insights summarize the data supporting new dosing recommendations for VTE prophylaxis in obese patients with cancer.

引用

页码：1079 / 1096

页数：18

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