Combined Electrochemistry and Surface-Enhanced Infrared Absorption Spectroscopy of Gramicidin A Incorporated into Tethered Bilayer Lipid Membranes

被引：59

作者：

Kozuch, Jacek ^{[1
]}

Steinem, Claudia ^{[3
]}

Hildebrandt, Peter ^{[1
]}

Millo, Diego ^{[2
]}

机构：

[1] Tech Univ Berlin, Inst Chem, D-10623 Berlin, Germany

[2] Vrije Univ Amsterdam, Biomol Spectroscopy LaserLaB Amsterdam, NL-1081 HV Amsterdam, Netherlands

[3] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 32期

关键词：

bilayer lipid membranes; electrochemistry; gramicidin A; ion channels; SEIRA; TRANSPORT; PROTEINS; CHANNELS; HELIX;

D O I：

10.1002/anie.201203214

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Support from the support: Tethered bilayer lipid membranes containing the cation-channel-forming peptide gramicidin A were assembled on nanostructured Au films. The combination of surface-enhanced infrared absorption (SEIRA) and electrochemical impedance spectroscopy (EIS) was used for the in situ structural and functional characterization of gramicidin A in the same device. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：8114 / 8117

页数：4

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