W. W. "Mo" Cleland: A Catalytic Life

被引：7

作者：

Dunaway-Mariano, Debra ^{[1
]}

Holden, Hazel M. ^{[2
]}

Raushel, Frank M. ^{[3
]}

机构：

[1] Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

[2] Univ Wisconsin, Dept Biochem, Madison, WI 53706 USA

[3] Texas A&M Univ, Dept Chem, College Stn, TX 77843 USA

来源：

BIOCHEMISTRY | 2013年 / 52卷 / 51期

关键词：

ENZYME; PRODUCTS; KINETICS; NOMENCLATURE; INHIBITION; HYDROLYSIS; MECHANISMS; ALKALINE;

D O I：

10.1021/bi4015709

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Professor W. Wallace Cleland, the architect of modern steadystate enzyme kinetics, died on March 6, 2013, from injuries sustained in a fall outside of his home. He will be most remembered for giving the enzyme community Ping-Pong kinetics and the invention of dithiothreitol (DTT). He pioneered the utilization of heavy atom isotope effects for the elucidation of the chemical mechanisms of enzyme-catalyzed reactions. His favorite research journal was Biochemistry, in which he published more than 135 papers beginning in 1964 with the disclosure

引用

页码：9092 / 9096

页数：5

共 26 条

[1] PRIMARY AND SECONDARY O-18 ISOTOPE EFFECTS IN THE ALKALINE AND ENZYME-CATALYZED HYDROLYSIS OF PHOSPHOTRIESTERS [J].

CALDWELL, SR ;

RAUSHEL, FM ;

WEISS, PM ;

CLELAND, WW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (02) :730-732

[2]

Cleland C. F., 2013, COMMUNICATION

[3]

Cleland W W, 1977, Adv Enzymol Relat Areas Mol Biol, V45, P273

[4]

Cleland W. W., 1977, CC/LIFE SCI, V27, P8

[5]

Cleland W. W., 1982, CC/LIFE SCI, V15, P20

[6]

CLELAND WW, 1960, J BIOL CHEM, V235, P45

[7] DITHIOTHREITOL NEW PROTECTIVE REAGENT FOR SH GROUPS [J].

CLELAND, WW .

BIOCHEMISTRY, 1964, 3 (04) :480-&

[8] COMPUTER PROGRAMMES FOR PROCESSING ENZYME KINETIC DATA [J].

CLELAND, WW .

NATURE, 1963, 198 (487) :463-+

[9]

CLELAND WW, 1956, J BIOL CHEM, V220, P595

[10]

CLELAND WW, 1954, J BIOL CHEM, V208, P679

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