Pseudoxanthoma Elasticum: Progress in Research Toward Treatment: Summary of the 2012 PXE International Research Meeting

被引：39
作者：
Uitto, Jouni [1 ]
Varadi, Andras [2 ]
Bercovitch, Lionel [3 ,4 ]
Terry, Patrick F. [4 ]
Terry, Sharon F. [4 ]
机构：
[1] Thomas Jefferson Univ, Jefferson Med Coll, Dept Dermatol & Cutaneous Biol, Philadelphia, PA 19107 USA
[2] Hungarian Acad Sci, Inst Enzymol, RCNS, Budapest, Hungary
[3] Brown Univ, Dept Dermatol, Alpert Med Sch, Providence, RI 02912 USA
[4] PXE Int, Washington, DC USA
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2013年 / 133卷 / 06期
关键词：
GENERALIZED ARTERIAL CALCIFICATION; CONNECTIVE-TISSUE MINERALIZATION; VITAMIN-K; MOUSE MODEL; ABCC6; GENE; ECTOPIC MINERALIZATION; EXPRESSION; MUTATIONS; INFANCY; MICE;
D O I：
10.1038/jid.2013.20
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：1444 / 1449
页数：6
相关论文
共 40 条
  • [1] The vitamin K-dependent carboxylase
    Berkner, KL
    [J]. ANNUAL REVIEW OF NUTRITION, 2005, 25 : 127 - 149
  • [2] A Single-Nucleotide Polymorphism in the Abcc6 Gene Associates with Connective Tissue Mineralization in Mice Similar to Targeted Models for Pseudoxanthoma Elasticum
    Berndt, Annerose
    Li, Qiaoli
    Potter, Christopher S.
    Liang, Yanhua
    Silva, Kathleen A.
    Kennedy, Victoria
    Uitto, Jouni
    Sundberg, John P.
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2013, 133 (03) : 833 - 836
  • [3] Does the absence of ABCC6 (multidrug resistance protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery?
    Borst, Piet
    van de Wetering, Koen
    Schlingemann, Reinier
    [J]. CELL CYCLE, 2008, 7 (11) : 1575 - 1579
  • [4] Vitamin K does not prevent soft tissue mineralization in a mouse model of pseudoxanthoma elasticum
    Brampton, Christopher
    Yamaguchi, Yukiko
    Vanakker, Olivier
    Van Laer, Lut
    Chen, Li-Hsieh
    Thakore, Manoj
    De Paepe, Anne
    Pomozi, Viola
    Szabo, Pal T.
    Martin, Ludovic
    Varadi, Andras
    Le Saux, Olivier
    [J]. CELL CYCLE, 2011, 10 (11) : 1810 - 1820
  • [5] The ERK1/2-Hepatocyte Nuclear Factor 4α Axis Regulates Human ABCC6 Gene Expression in Hepatocytes
    de Boussac, Hugues
    Ratajewski, Marcin
    Sachrajda, Iwona
    Koblos, Gabriella
    Tordai, Attila
    Pulaski, Lukasz
    Buday, Laszlo
    Varadi, Andras
    Aranyi, Tamas
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (30) : 22798 - 22806
  • [6] ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: Relevance to pathomechanisms of pseudoxanthoma elasticum
    Fueloep, Krisztina
    Jiang, Qiujie
    Wetering, Koen V. D.
    Pomozi, Viola
    Szabo, Pal T.
    Aranyi, Tamas
    Sarkadi, Balazs
    Borst, Piet
    Uitto, Jouni
    Varadi, Andras
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 415 (03) : 468 - 471
  • [7] Pseudoxanthoma elasticum, ocular manifestations, complications and treatment
    Georgalas, Ilias
    Tservakis, Ioannis
    Papaconstaninou, Dimitris
    Kardara, Marina
    Koutsandrea, Chryssanthi
    Ladas, Ioannis
    [J]. CLINICAL AND EXPERIMENTAL OPTOMETRY, 2011, 94 (02) : 169 - 180
  • [8] Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum
    Gorgels, TGMF
    Hu, XF
    Scheffer, GL
    van der Wal, AC
    Toonstra, J
    de Jong, PTVM
    van Kuppevelt, TH
    Levelt, CN
    de Wolf, A
    Loves, WJP
    Scheper, RJ
    Peek, R
    Bergen, AAB
    [J]. HUMAN MOLECULAR GENETICS, 2005, 14 (13) : 1763 - 1773
  • [9] Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum
    Gorgels, Theo G. M. F.
    Waarsing, Jan H.
    Herfs, Marjolein
    Versteeg, Danielle
    Schoensiegel, Frank
    Sato, Toshiro
    Schlingemann, Reinier O.
    Ivandic, Boris
    Vermeer, Cees
    Schurgers, Leon J.
    Bergen, Arthur A. B.
    [J]. JOURNAL OF MOLECULAR MEDICINE-JMM, 2011, 89 (11): : 1125 - 1135
  • [10] Administration of Bone Marrow Derived Mesenchymal Stem Cells into the Liver: Potential to Rescue Pseudoxanthoma Elasticum in a Mouse Model (Abcc6-/-)
    Jiang, Qiujie
    Takahagi, Shunsuke
    Uitto, Jouni
    [J]. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2012,
1234