Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides

被引：52

作者：

Bereman, Michael S. ^{[1
]}

Comins, Daniel L. ^{[1
]}

Muddiman, David C. ^{[1
]}

机构：

[1] N Carolina State Univ, Dept Chem, WM Keck FTICR Mass Spectrometry Lab, Raleigh, NC 27695 USA

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 02期

关键词：

MASS-SPECTROMETRY; TRIMETHYLSILYL DERIVATIVES; QUANTITATIVE-ANALYSIS; TAGS; PEPTIDES; ENERGY; OLIGOSACCHARIDES;

D O I：

10.1039/b915589a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel tags are used to increase the hydrophobicity of glycans and impart a permanent charge yielding as great as a similar to 5-fold increase in electrospray response from both a standard and complex mixture.

引用

页码：237 / 239

页数：3

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