Bioinspired Multifunctional Protein Coating for Antifogging, Self-Cleaning, and Antimicrobial Properties

被引:71
|
作者
Qi, Haishan [1 ,2 ,3 ]
Zhang, Chen [1 ,2 ,3 ]
Guo, Hongshuang [1 ,2 ,3 ]
Zheng, Weiwei [1 ,2 ,3 ]
Yang, Jing [1 ,2 ,3 ]
Zhou, Xiao [1 ,2 ,3 ]
Zhang, Lei [1 ,2 ,3 ,4 ]
机构
[1] Tianjin Univ, Dept Biochem Engn, Sch Chem Engn & Technol, Tianjin 300350, Peoples R China
[2] Tianjin Univ, Frontier Sci Ctr Synthet Biol, Sch Chem Engn & Technol, Tianjin 300350, Peoples R China
[3] Tianjin Univ, Key Lab Syst Bioengn MOE, Sch Chem Engn & Technol, Tianjin 300350, Peoples R China
[4] Tianjin Univ, Qingdao Inst Marine Technol, Qingdao 266235, Shandong, Peoples R China
基金
中国国家自然科学基金;
关键词
3,4-dihydroxyphenylalanine; posttranslational modification; protein engineering; surface chemistry; universal; multifunctional protein coating; antifogging; self-cleaning; antimicrobial; biocompatibility; ANTI-FOG SURFACES; UNDERWATER SUPEROLEOPHOBICITY; POLY(ETHYLENE GLYCOL); BACTERIAL ADHESION; ANTIBACTERIAL; MUSSEL; FILMS; DOPA; FABRICATION; MEMBRANES;
D O I
10.1021/acsami.9b03522
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
A multifunctional coating with antifogging, self-cleaning, and antimicrobial properties has been prepared based on a mussel-inspired chimeric protein MP-KE, which is the first example that these proteins were successfully applied to fabricate antifogging surfaces. The coating exhibits super hydrophilic properties, as indicated by contact angles less than 5 degrees and high light transmittance similar to bare glass substrates about 90%. The zwitterionic peptides of MP-KE empower water molecules to expand into thin hydrated films rapidly, providing the protein coating with diverse surface functions. Moreover, the coatings have excellent stability and a convenient preparation process because of the mussel adhesive motif of MP-KE which makes the coating anchor onto the surface strongly. As a protein material, this multifunctional coating possesses remarkable biocompatibility and has potential application prospects in the biomedical and pharmaceutical fields.
引用
收藏
页码:24504 / 24511
页数:8
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