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Bioinspired Multifunctional Protein Coating for Antifogging, Self-Cleaning, and Antimicrobial Properties
被引:71
|作者:
Qi, Haishan
[1
,2
,3
]
Zhang, Chen
[1
,2
,3
]
Guo, Hongshuang
[1
,2
,3
]
Zheng, Weiwei
[1
,2
,3
]
Yang, Jing
[1
,2
,3
]
Zhou, Xiao
[1
,2
,3
]
Zhang, Lei
[1
,2
,3
,4
]
机构:
[1] Tianjin Univ, Dept Biochem Engn, Sch Chem Engn & Technol, Tianjin 300350, Peoples R China
[2] Tianjin Univ, Frontier Sci Ctr Synthet Biol, Sch Chem Engn & Technol, Tianjin 300350, Peoples R China
[3] Tianjin Univ, Key Lab Syst Bioengn MOE, Sch Chem Engn & Technol, Tianjin 300350, Peoples R China
[4] Tianjin Univ, Qingdao Inst Marine Technol, Qingdao 266235, Shandong, Peoples R China
基金:
中国国家自然科学基金;
关键词:
3,4-dihydroxyphenylalanine;
posttranslational modification;
protein engineering;
surface chemistry;
universal;
multifunctional protein coating;
antifogging;
self-cleaning;
antimicrobial;
biocompatibility;
ANTI-FOG SURFACES;
UNDERWATER SUPEROLEOPHOBICITY;
POLY(ETHYLENE GLYCOL);
BACTERIAL ADHESION;
ANTIBACTERIAL;
MUSSEL;
FILMS;
DOPA;
FABRICATION;
MEMBRANES;
D O I:
10.1021/acsami.9b03522
中图分类号:
TB3 [工程材料学];
学科分类号:
0805 ;
080502 ;
摘要:
A multifunctional coating with antifogging, self-cleaning, and antimicrobial properties has been prepared based on a mussel-inspired chimeric protein MP-KE, which is the first example that these proteins were successfully applied to fabricate antifogging surfaces. The coating exhibits super hydrophilic properties, as indicated by contact angles less than 5 degrees and high light transmittance similar to bare glass substrates about 90%. The zwitterionic peptides of MP-KE empower water molecules to expand into thin hydrated films rapidly, providing the protein coating with diverse surface functions. Moreover, the coatings have excellent stability and a convenient preparation process because of the mussel adhesive motif of MP-KE which makes the coating anchor onto the surface strongly. As a protein material, this multifunctional coating possesses remarkable biocompatibility and has potential application prospects in the biomedical and pharmaceutical fields.
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页码:24504 / 24511
页数:8
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