The role of protective effects of proline-containing peptides (PGP, PG, and GP) in contractile dysfunction of mesenteric lymphatic vessels in rats with experimental acute peritonitis

被引：11

作者：

Umarova, B. A. ^{[1
]}

Lelekova, T. V. ^{[1
]}

Kopylova, G. N. ^{[1
]}

Goncharova, E. L. ^{[1
]}

Bakaeva, Z. V. ^{[1
]}

Samonina, G. V. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Biol, Dept Human & Anim Physiol, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2006年 / 142卷 / 03期

关键词：

inflammation; lymphatic vessels; glyprolines;

D O I：

10.1007/s10517-006-0346-2

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The development of acute peritonitis in rats induced by intraperitoneal injection of thioglycollate was accompanied by a decrease in contractile function of mesenteric lymphatic vessels and impaired response to norepinephrine. Administration of proline-containing peptides after induction of inflammation significantly decreased the severity of these disorders. Our results attest to the possibility of using peptides for the correction of mesenteric microcirculatory disturbances during inflammation.

引用

页码：279 / 282

页数：4

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