The role of hyperthermia as a treatment for non-muscle invasive bladder cancer
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作者:
Bahouth, Zaher
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Technion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, IsraelTechnion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, Israel
Bahouth, Zaher
[1
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Halachmi, Sarel
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Technion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, IsraelTechnion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, Israel
Halachmi, Sarel
[1
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Moskovitz, Boaz
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Technion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, IsraelTechnion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, Israel
Moskovitz, Boaz
[1
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Nativ, Ofer
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Technion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, IsraelTechnion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, Israel
Nativ, Ofer
[1
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机构:
[1] Technion Israel Inst Technol, Fac Med, Dept Urol, Bnai Zion Med Ctr, Haifa, Israel
Non-muscle invasive bladder cancer (NMIBC) has a high tendency for recurrence and progression. Currently, all known intravesical agents are associated with adverse effects (AEs) and limited efficacy. The combination of hyperthermia (HT) with intravesical Mitomycin C (MMC) chemotherapy has been shown to improve outcomes. The added efficacy of HT to MMC was first shown in preclinical studies. The reports on patients with NMIBC have indicated that the treatment is safe and well tolerated. Several clinical studies reported the efficacy of radiofrequency-induced chemotherapy effect (RITE) in the treatment of patients with NMIBC. This modality was shown to be superior to MMC alone. RITE was effective also in patients with high-risk NMIBC, including those who failed Bacillus Calmette-Guerin (BCG). This study provides an updated review of literature regarding the use of RITE in patients with NMIBC.
机构:
Columbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USAColumbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USA
Barlow, LaMont J.
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McKiernan, James M.
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Columbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USAColumbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USA
McKiernan, James M.
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Benson, Mitchell C.
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Columbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USAColumbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USA
机构:
Columbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USAColumbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USA
Barlow, LaMont J.
;
McKiernan, James M.
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Columbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USAColumbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USA
McKiernan, James M.
;
Benson, Mitchell C.
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Columbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USAColumbia Univ, New York Presbyterian Hosp, Med Ctr, Dept Urol, New York, NY USA