The opioid and related drug epidemics in rural Appalachia: A systematic review of populations affected, risk factors, and infectious diseases
被引:59
作者:
Schalkoff, Christine A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USAUniv North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
Schalkoff, Christine A.
[1
]
Lancaster, Kathryn E.
论文数: 0引用数: 0
h-index: 0
机构:
Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USAUniv North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
Lancaster, Kathryn E.
[2
]
Gaynes, Bradley N.
论文数: 0引用数: 0
h-index: 0
机构:
Univ North Carolina Chapel Hill, UNC Sch Med, Dept Psychiat, Chapel Hill, NC USAUniv North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
Gaynes, Bradley N.
[3
]
Wang, Vivian
论文数: 0引用数: 0
h-index: 0
机构:
Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USAUniv North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
Wang, Vivian
[2
]
Pence, Brian W.
论文数: 0引用数: 0
h-index: 0
机构:
Univ North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USAUniv North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
Pence, Brian W.
[1
]
Miller, William C.
论文数: 0引用数: 0
h-index: 0
机构:
Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USAUniv North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
Miller, William C.
[2
]
Go, Vivian F.
论文数: 0引用数: 0
h-index: 0
机构:
Univ North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USAUniv North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
Go, Vivian F.
[1
]
机构:
[1] Univ North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
[2] Ohio State Univ, Coll Publ Hlth, Columbus, OH 43210 USA
[3] Univ North Carolina Chapel Hill, UNC Sch Med, Dept Psychiat, Chapel Hill, NC USA
Background/aims: To examine trends in rural Appalachian opioid and related drug epidemics during the past 10 years, including at-risk populations, substance use shifts and correlates, and associated infections. Methods: We conducted this review in accordance with the Preferred Reporting Items for Systematic Reviews (PRISMA) guidelines. Seven databases were searched for quantitative studies, published between January 2006 and December 2017, of drug use, drug-related mortality, or associated infections in rural Appalachia. Results: Drug-related deaths increased in study states, and a high incidence of polydrug toxicity was noted. Rural substance use was most common among young, white males, with low education levels. A history of depression/anxiety was common among study populations. Prescription opioids were most commonly used, often in conjunction with sedatives. Women emerged as a distinct user subpopulation, with different routes of drug use initiation and drug sources. Injection drug use was accompanied by risky injection behaviors and was associated with hepatitis C. Conclusions: This review can help to inform substance use intervention development and implementation in rural Appalachian populations. Those at highest risk are young, white males who often engage in polysubstance use and have a history of mental health issues. Differences in risk factors among other groups and characteristics of drug use in rural Appalachian populations that are conducive to human immunodeficiency virus (HIV) spread also warrant consideration.
机构:
Univ Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
Christian, W. Jay
Hopenhayn, Claudia
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
Univ Kentucky, Coll Publ Hlth, Lexington, KY 40504 USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
Hopenhayn, Claudia
Christian, Amy
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
Christian, Amy
McIntosh, Deana
论文数: 0引用数: 0
h-index: 0
机构:
Kentucky River Dist Hlth Dept, Hazard, KY USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
McIntosh, Deana
Koch, Alvaro
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Albert B Chandler Med Ctr, Dept Internal Med, Lexington, KY 40504 USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
机构:
Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
W Virginia Dept Hlth & Human Resources, Div Surveillance & Dis Control, Charleston, WV USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Hall, Aron J.
Logan, Joseph E.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Logan, Joseph E.
Toblin, Robin L.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Toblin, Robin L.
Kaplan, James A.
论文数: 0引用数: 0
h-index: 0
机构:
W Virginia Dept Hlth & Human Resources, Off Chief Med Examiner, Charleston, WV USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Kaplan, James A.
Kraner, James C.
论文数: 0引用数: 0
h-index: 0
机构:
W Virginia Dept Hlth & Human Resources, Off Chief Med Examiner, Charleston, WV USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Kraner, James C.
Bixler, Danae
论文数: 0引用数: 0
h-index: 0
机构:
W Virginia Dept Hlth & Human Resources, Div Surveillance & Dis Control, Charleston, WV USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Bixler, Danae
Crosby, Alex E.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Crosby, Alex E.
Paulozzi, Leonard J.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Paulozzi, Leonard J.
[J].
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION,
2008,
300
(22):
: 2613
-
2620
机构:
Univ Louisville, Kent Sch Social Work, Louisville, KY 40292 USAUniv Louisville, Kent Sch Social Work, Louisville, KY 40292 USA
Hall, Martin T.
Leukefeld, Carl G.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Coll Med, Dept Behav Sci, Lexington, KY 40536 USA
Univ Kentucky, Coll Med, Ctr Drug & Alcohol Res, Lexington, KY USAUniv Louisville, Kent Sch Social Work, Louisville, KY 40292 USA
Leukefeld, Carl G.
Havens, Jennifer R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Coll Med, Dept Behav Sci, Lexington, KY 40536 USA
Univ Kentucky, Coll Med, Ctr Drug & Alcohol Res, Lexington, KY USAUniv Louisville, Kent Sch Social Work, Louisville, KY 40292 USA
机构:
Univ Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
Christian, W. Jay
Hopenhayn, Claudia
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
Univ Kentucky, Coll Publ Hlth, Lexington, KY 40504 USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
Hopenhayn, Claudia
Christian, Amy
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
Christian, Amy
McIntosh, Deana
论文数: 0引用数: 0
h-index: 0
机构:
Kentucky River Dist Hlth Dept, Hazard, KY USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
McIntosh, Deana
Koch, Alvaro
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Albert B Chandler Med Ctr, Dept Internal Med, Lexington, KY 40504 USAUniv Kentucky, Coll Med, Markey Canc Control Program, Lexington, KY 40504 USA
机构:
Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
W Virginia Dept Hlth & Human Resources, Div Surveillance & Dis Control, Charleston, WV USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Hall, Aron J.
Logan, Joseph E.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Logan, Joseph E.
Toblin, Robin L.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Toblin, Robin L.
Kaplan, James A.
论文数: 0引用数: 0
h-index: 0
机构:
W Virginia Dept Hlth & Human Resources, Off Chief Med Examiner, Charleston, WV USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Kaplan, James A.
Kraner, James C.
论文数: 0引用数: 0
h-index: 0
机构:
W Virginia Dept Hlth & Human Resources, Off Chief Med Examiner, Charleston, WV USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Kraner, James C.
Bixler, Danae
论文数: 0引用数: 0
h-index: 0
机构:
W Virginia Dept Hlth & Human Resources, Div Surveillance & Dis Control, Charleston, WV USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Bixler, Danae
Crosby, Alex E.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Crosby, Alex E.
Paulozzi, Leonard J.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Natl Ctr Injury Prevent & Control, Atlanta, GA 30333 USACtr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA 30333 USA
Paulozzi, Leonard J.
[J].
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION,
2008,
300
(22):
: 2613
-
2620
机构:
Univ Louisville, Kent Sch Social Work, Louisville, KY 40292 USAUniv Louisville, Kent Sch Social Work, Louisville, KY 40292 USA
Hall, Martin T.
Leukefeld, Carl G.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Coll Med, Dept Behav Sci, Lexington, KY 40536 USA
Univ Kentucky, Coll Med, Ctr Drug & Alcohol Res, Lexington, KY USAUniv Louisville, Kent Sch Social Work, Louisville, KY 40292 USA
Leukefeld, Carl G.
Havens, Jennifer R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kentucky, Coll Med, Dept Behav Sci, Lexington, KY 40536 USA
Univ Kentucky, Coll Med, Ctr Drug & Alcohol Res, Lexington, KY USAUniv Louisville, Kent Sch Social Work, Louisville, KY 40292 USA