Hypoglycemic and hypolipidemic effects of aqueous extract of Arachis hypogaea in normal and alloxan-induced diabetic rats

被引:19
作者
Bilbis, LS
Shehu, RA
Abubakar, AG [1 ]
机构
[1] Univ Surrey, Sch Biomed & Life Sci, Surrey GU2 7XH, England
[2] Usmanu Dandofiyo Univ Sokoto, Dept Biochem, Sokoto, Nigeria
关键词
Arachis hypogaea; diabetics; hypoglycemia; hypolipidemia; alloxan; triglyceride; cholesterol;
D O I
10.1078/09447110260573191
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The hypoglycemic and hypolipidemic effect of aqueous extract of Arachis hypogaea was investigated in normal and alloxan-induced diabetic rats. The extract caused a significant (P < 0.05) decrease of fasting blood glucose of both normal and alloxan-induced diabetic rats from 102.60 +/- 1.65 mg/dl to 88.79 +/- 0.94 mg/dl for normal and 189.0 +/- 30.79 mg/dl to 107.55 +/- 1.54 mg/dl for alloxan-induced diabetic rats. The extract also caused a significant (P < 0.05) decrease in serum triglyceride, total cholesterol, HDL-cholesterol and LDL-cholesterol in both normal and alloxan-induced diabetic rats.
引用
收藏
页码:553 / 555
页数:3
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