Pharmacological profile of green tea and its polyphenols: a review

被引:52
作者
Bansal, Sumit [1 ]
Syan, Navneet [1 ]
Mathur, Pooja [1 ]
Choudhary, Shivani [2 ]
机构
[1] Ganpati Inst Pharm, Dept Pharmaceut Chem, Yamunanagar 135102, Haryana, India
[2] Doon Valley Inst Pharm & Med, Karnal 132001, Haryana, India
关键词
Catechins; Epigallocatechin-3-gallate (EGCG); Green Tea; Polyphenols; EPIGALLOCATECHIN GALLATE; (-)-EPIGALLOCATECHIN GALLATE; OXIDATIVE-STRESS; ANTIOXIDANT ACTIVITY; PRECURSOR PROTEIN; INDUCED GASTRITIS; BLOOD-PRESSURE; CANCER RISK; BLACK TEA; CATECHINS;
D O I
10.1007/s00044-011-9800-4
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Tea (Camellia sinensis, Theaceae) is the second most consumed beverages in the world, next to water in terms of worldwide popularity. The chemical components of green tea chiefly include polyphenols, caffeine, and amino acids. Green tea is rich in catechins, of which (-)-epigallocatechin-3-gallate is the most abundant. As described in literature, green tea and its polyphenols are beneficial in curing a wide variety of diseases like cancer, diabetes, cardiovascular disease, obesity, etc. It also has antimicrobial activity, protects from solar radiations, and possesses neuroprotective properties. The current review article focuses on pharmacological profile associated with Green tea and its polyphenols. We hope that this review will expose areas for further study and encourage research on important public health issue.
引用
收藏
页码:3347 / 3360
页数:14
相关论文
共 105 条
  • [81] Epicatechin gallate, a component of green tea, reduces halotolerance in Staphylococcus aureus
    Stapleton, Paul D.
    Gettert, Jasmine
    Taylor, Peter W.
    [J]. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2006, 111 (03) : 276 - 279
  • [82] Green tea inhibits Helicobacter growth in vivo and in vitro
    Stoicov, Calin
    Saffari, Reza
    Houghton, JeanMarie
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2009, 33 (05) : 473 - 478
  • [83] Suganuma M, 1999, CANCER RES, V59, P44
  • [84] Neuroprotective effects of (-)-epigallocatechin gallate after hypoxia-ischemia-induced brain damage: novel mechanisms of action
    Sutherland, BA
    Shaw, OM
    Clarkson, AN
    Jackson, DM
    Sammut, IA
    Appleton, I
    [J]. FASEB JOURNAL, 2004, 18 (14) : 258 - +
  • [85] (-)-Epigallocatechin-3-gallate suppresses growth of AZ521 human gastric cancer cells by targeting the DEAD-box RNA helicase p68
    Tanaka, Tomoko
    Ishii, Takeshi
    Mizuno, Daisuke
    Mori, Taiki
    Yamaji, Ryoichi
    Nakamura, Yoshimasa
    Kumazawa, Shigenori
    Nakayama, Tsutomu
    Akagawa, Mitsugu
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2011, 50 (10) : 1324 - 1335
  • [86] Taylor Peter W, 2005, Food Sci Technol Bull, V2, P71, DOI 10.1616/1476-2137.14184
  • [87] Green tea and the risk of gastric cancer in Japan.
    Tsubono, Y
    Nishino, Y
    Komatsu, S
    Hsieh, C
    Kanemura, S
    Tsuji, I
    Nakatsuka, H
    Fukao, A
    Satoh, H
    Hisamichi, S
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (09) : 632 - 636
  • [88] Green tea Polyphenol epigallocatechin-3-gallate signaling pathway through 67-kDa laminin receptor
    Umeda, Daisuke
    Yano, Satomi
    Yamada, Koji
    Tachibana, Hirofumi
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (06) : 3050 - 3058
  • [89] USDA website, USDA DAT FLAV CONT S
  • [90] Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production
    Waltner-Law, ME
    Wang, XHL
    Law, BK
    Hall, RK
    Nawano, M
    Granner, DK
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (38) : 34933 - 34940