Pharmacological profile of green tea and its polyphenols: a review

被引：52
作者：
Bansal, Sumit [1 ]
Syan, Navneet [1 ]
Mathur, Pooja [1 ]
Choudhary, Shivani [2 ]
机构：
[1] Ganpati Inst Pharm, Dept Pharmaceut Chem, Yamunanagar 135102, Haryana, India
[2] Doon Valley Inst Pharm & Med, Karnal 132001, Haryana, India
来源：
MEDICINAL CHEMISTRY RESEARCH | 2012年 / 21卷 / 11期
关键词：
Catechins; Epigallocatechin-3-gallate (EGCG); Green Tea; Polyphenols; EPIGALLOCATECHIN GALLATE; (-)-EPIGALLOCATECHIN GALLATE; OXIDATIVE-STRESS; ANTIOXIDANT ACTIVITY; PRECURSOR PROTEIN; INDUCED GASTRITIS; BLOOD-PRESSURE; CANCER RISK; BLACK TEA; CATECHINS;
D O I：
10.1007/s00044-011-9800-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Tea (Camellia sinensis, Theaceae) is the second most consumed beverages in the world, next to water in terms of worldwide popularity. The chemical components of green tea chiefly include polyphenols, caffeine, and amino acids. Green tea is rich in catechins, of which (-)-epigallocatechin-3-gallate is the most abundant. As described in literature, green tea and its polyphenols are beneficial in curing a wide variety of diseases like cancer, diabetes, cardiovascular disease, obesity, etc. It also has antimicrobial activity, protects from solar radiations, and possesses neuroprotective properties. The current review article focuses on pharmacological profile associated with Green tea and its polyphenols. We hope that this review will expose areas for further study and encourage research on important public health issue.
引用
收藏
页码：3347 / 3360
页数：14
相关论文
共 105 条
  • [1] Abdel-Raheem IT, 2010, PAK J PHARM SCI, V23, P21
  • [2] Nitric Oxide Releasing Derivatives of [(2-Chloroethyl)ureido] Benzoic Acid Esters as Potential Antineoplastic Agents
    Akgun, Hulya
    Berk, Barkin
    Erol, Dilek Demir
    Mercanoglu, Guldem
    Bayrak, Omer Faruk
    Caglayan, Berrak
    Dedeagac, Asli
    Kurnaz, Isil Aksan
    [J]. TURKISH JOURNAL OF CHEMISTRY, 2009, 33 (01) : 107 - 121
  • [3] Green tea epigallocatechin-3-gallate mediates T cellular NF-κB inhibition and exerts neuroprotection in autoimmune encephalomyelitis
    Aktas, O
    Prozorovski, T
    Smorodchenko, A
    Savaskan, NE
    Lauster, R
    Kloetzel, PM
    Infante-Duarte, C
    Brocke, S
    Zipp, F
    [J]. JOURNAL OF IMMUNOLOGY, 2004, 173 (09) : 5794 - 5800
  • [4] Al-Attar Atef M, 2010, Saudi J Biol Sci, V17, P295, DOI 10.1016/j.sjbs.2010.05.007
  • [5] Tea and herbal infusions: Their antioxidant activity and phenolic profile
    Atoui, AK
    Mansouri, A
    Boskou, G
    Kefalas, P
    [J]. FOOD CHEMISTRY, 2005, 89 (01) : 27 - 36
  • [6] Antimicrobial activity of rationally designed amino terminal modified peptides
    Bisht, Gopal Singh
    Rawat, Diwan S.
    Kumar, Anil
    Kumar, Rita
    Pasha, Santosh
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (15) : 4343 - 4346
  • [7] Epigallocatechin gallate inhibits biofilm formation by ocular staphylococcal isolates
    Blanco, AR
    Sudano-Roccaro, A
    Spoto, GC
    Nostro, A
    Rusciano, D
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (10) : 4339 - 4343
  • [8] The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: A pilot study
    Boschmann, Michael
    Thielecke, Frank
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 2007, 26 (04) : 389S - 395S
  • [9] The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice
    Bose, Mousumi
    Lambert, Joshua D.
    Ju, Jihyeung
    Reuhl, Kenneth R.
    Shapses, Sue A.
    Yang, Chung S.
    [J]. JOURNAL OF NUTRITION, 2008, 138 (09) : 1677 - 1683
  • [10] Beneficial effects of green tea -: A review
    Cabrera, C
    Artacho, R
    Giménez, R
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 2006, 25 (02) : 79 - 99
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