THE INFLUENCE OF TERPENES ON HUMAN STRATUM CORNEUM BY FLUORESCENCE MICROSCOPY, ATOMIC FORCE MICROSCOPY AND SCANNING ELECTRON MICROSCOPY

被引：0

作者：

Cal, Krzysztof ^{[1
]}

Stefanowska, Justyna ^{[1
]}

Govedarica, Biljana ^{[2
]}

Planinsek, Odon ^{[2
]}

Srcic, Stane ^{[2
]}

Bazela, Karolina ^{[3
]}

Debowska, Renata ^{[3
]}

机构：

[1] Med Univ Gdansk, Dept Pharmaceut Technol, Hallera 107, PL-80416 Gdansk, Poland

[2] Univ Ljubljana, Fac Pharm, Dept Pharmaceut Technol, Askerceva 7, SI-1000 Ljubljana, Slovenia

[3] Dr Irena Eris Ctr Sci & Res, Pulawska 107A, PL-02595 Warsaw, Poland

来源：

ACTA POLONIAE PHARMACEUTICA | 2017年 / 74卷 / 04期

关键词：

terpenes; stratum comeum; AFM; SEM; fluorescence microscopy; irritation test; SKIN PENETRATION ENHANCEMENT; IN-VITRO;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Numerous preparations containing single terpenes or complexes of essential oils are applied onto the skin in their pure form or in the form of ointments, gels, oily solutions, etc. The aim of this study was to visualize changes in the stratum contemn by terpinen-4-ol. racemic camphor, eucalyptol, racemic menthol and levomenthol incorporated in various concentrations into lipophilic, ethanolic or hydrophilic vehicle. Additionally. an initation in vitro test was performed to determine the influence of individual formulations and pure vehicles on viability of skin cells.

引用

页码：1063 / 1070

页数：8

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