The Nucleosome Family: Dynamic and Growing

被引：132

作者：

Zlatanova, Jordanka ^{[1
]}

Bishop, Thomas C. ^{[2
]}

Victor, Jean-Marc ^{[3
,4
]}

Jackson, Vaughn ^{[5
]}

van Holde, Ken ^{[6
]}

机构：

[1] Univ Wyoming, Dept Mol Biol, Laramie, WY 82071 USA

[2] Tulane Univ, Ctr Compuatat Sci, New Orleans, LA 70118 USA

[3] Univ Paris 06, UPMC, F-75252 Paris, France

[4] CNRS, UMR 7600, Lab Phys Theor Matiere Condensee, F-75252 Paris 5, France

[5] Med Coll Wisconsin, Dept Biochem, Milwaukee, WI 53226 USA

[6] Oregon State Univ, Dept Biochem & Biophys, Corvallis, OR 97331 USA

来源：

STRUCTURE | 2009年 / 17卷 / 02期

基金：

美国国家科学基金会;

关键词：

RNA-POLYMERASE-II; HISTONE (H3-H4)(2) TETRAMER; SINGLE CHROMATIN FIBERS; CORE PARTICLE; ANGSTROM RESOLUTION; IN-VIVO; PREFERENTIAL BINDING; ASSEMBLY PROTEIN-1; REVERSIBLE CHANGES; ARCHAEAL HISTONES;

D O I：

10.1016/j.str.2008.12.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ever since the discovery of the nucleosome in 1974, scientists have stumbled upon discrete particles in which DNA is wrapped around histone complexes of different stoichiometries: octasomes, hexasomes, tetrasomes, "split" half-nucleosomes, and, recently, bona fide hemisomes. Do all these particles exist in vivo? Under what conditions? What is their physiological significance in the complex DNA transactions in the eukaryotic nucleus? What are their dynamics? This review summarizes research spanning more than three decades and provides a new meaning to the term "nucleosome." The nucleosome can no longer be viewed as a single static entity: rather, it is a family of particles differing in their structural and dynamic properties, leading to different functionalities.

引用

页码：160 / 171

页数：12

共 101 条

[1] Nucleosome dynamics IV.: Protein and DNA contributions in the chiral transition of the tetrasome, the histone (H3-H4)2 tetramer-DNA particle [J].

Alilat, M ;

Sivolob, A ;

Révet, B ;

Prunell, A .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 291 (04) :815-841

[2] NUCLEASE CLEAVAGE OF CHROMATIN AT 100-NUCLEOTIDE PAIR INTERVALS [J].

ALTENBURGER, W ;

HORZ, W ;

ZACHAU, HG .

NATURE, 1976, 264 (5586) :517-522

[3] Split decision: What happens to nucleosomes during DNA replication? [J].

Annunziato, AT .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (13) :12065-12068

[4] Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro [J].

Asahara, H ;

Tartare-Deckert, S ;

Nakagawa, T ;

Ikehara, T ;

Hirose, F ;

Hunter, T ;

Ito, T ;

Montminy, M .

MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (09) :2974-2983

[5] EUKARYOTIC RNA POLYMERASE-II BINDS TO NUCLEOSOME CORES FROM TRANSCRIBED GENES [J].

BAER, BW ;

RHODES, D .

NATURE, 1983, 301 (5900) :482-488

[6] Structural plasticity of single chromatin fibers revealed by torsional manipulation [J].

Bancaud, A ;

Silva, NCE ;

Barbi, M ;

Wagner, G ;

Allemand, JF ;

Mozziconacci, J ;

Lavelle, C ;

Croquette, V ;

Victor, JM ;

Prunell, A ;

Viovy, JL .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2006, 13 (05) :444-450

[7] Nucleosome chiral transition under positive torsional stress in single chromatin fibers [J].

Bancaud, Aurelien ;

Wagner, Gaudeline ;

Conde e Silva, Natalia ;

Lavelle, Christophe ;

Wong, Hua ;

Mozziconacci, Julien ;

Barbi, Maria ;

Sivolob, Andrei ;

Le Cam, Eric ;

Mouawad, Liliane ;

Viovy, Jean-Louis ;

Victor, Jean-Marc ;

Prunell, Ariel .

MOLECULAR CELL, 2007, 27 (01) :135-147

[8] Folding mechanism of the (H3-H4)2 histone tetramer of the core nucleosome [J].

Banks, DD ;

Gloss, LM .

PROTEIN SCIENCE, 2004, 13 (05) :1304-1316

[9] Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA [J].

Bao, YH ;

Konesky, K ;

Park, YJ ;

Rosu, S ;

Dyer, PN ;

Rangasamy, D ;

Tremethick, DJ ;

Laybourn, PJ ;

Luger, K .

EMBO JOURNAL, 2004, 23 (16) :3314-3324

[10] Visualization and analysis of unfolded nucleosomes associated with transcribing chromatin [J].

BazettJones, DP ;

Mendez, E ;

Czarnota, GJ ;

Ottensmeyer, FP ;

Allfrey, VG .

NUCLEIC ACIDS RESEARCH, 1996, 24 (02) :321-329

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