Batch fabrication of micro-coils for MR spectroscopy on silicon

被引:0
作者
Syms, RRA [1 ]
Ahmad, MM [1 ]
Young, IR [1 ]
Gilderdale, D [1 ]
Collins, DJ [1 ]
Leach, MO [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, EEE Dept, London SW7 2AZ, England
来源
2005 IEEE SENSORS, VOLS 1 AND 2 | 2005年
关键词
D O I
暂无
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
A process for batch fabrication of low-cost microcoils for magnetic resonance (MR) spectroscopy of clinical biopsy samples is demonstrated. Conductors are fabricated on oxidized, intrinsic silicon substrates by electroplating metals inside a deep photoresist mould. Through-wafer deep reactive ion etching (DRIE) is used to define precise sample volumes and stencil cuts around each die, and dies are separated by snap-out. Single- and multiple-coil (Helm holtz-type) sensors are formed, by stacking parts on silicon baseplates. MR imaging and spectroscopy are both demonstrated on model samples, with high SNR.
引用
收藏
页码:227 / 230
页数:4
相关论文
共 13 条
[1]  
Barton SJ, 1999, MAGN RESON MATER PHY, V8, P121
[2]   Development of implantable detection microcoils for minimally invasive NMR spectroscopy [J].
Berry, L ;
Renaud, L ;
Kleimann, P ;
Morin, P ;
Armenean, M ;
Saint-Jalmes, H .
SENSORS AND ACTUATORS A-PHYSICAL, 2001, 93 (03) :214-218
[3]  
Bhardwaj JK, 1995, P SOC PHOTO-OPT INS, V2639, P224, DOI 10.1117/12.221279
[4]   SU-8 thick photoresist processing as a functional material for MEMS applications [J].
Conradie, EH ;
Moore, DF .
JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2002, 12 (04) :368-374
[5]   Integrated and interactive position tracking and imaging of interventional tools and internal devices using small fiducial receiver coils [J].
Coutts, GA ;
Gilderdale, DJ ;
Chui, M ;
Kasuboski, L ;
DeSouza, NM .
MAGNETIC RESONANCE IN MEDICINE, 1998, 40 (06) :908-913
[6]   Preamplified planar microcoil on GaAs substrates for microspectroscopy [J].
Dechow, J ;
Lanz, T ;
Stumber, M ;
Forchel, A ;
Haase, A .
REVIEW OF SCIENTIFIC INSTRUMENTS, 2003, 74 (11) :4855-4857
[7]   Fabrication of NMR - microsensors for nanoliter sample volumes [J].
Dechow, J ;
Forchel, A ;
Lanz, T ;
Haase, A .
MICROELECTRONIC ENGINEERING, 2000, 53 (1-4) :517-519
[8]   Design and use of internal receiver coils for magnetic resonance imaging [J].
Gilderdale, DJ ;
deSouza, NM ;
Coutts, GA ;
Chui, MK ;
Larkman, DJ ;
Williams, AD ;
Young, IR .
BRITISH JOURNAL OF RADIOLOGY, 1999, 72 (864) :1141-1151
[9]   High-Q factor RF planar microcoils for micro-scale NMR spectroscopy [J].
Massin, C ;
Boero, C ;
Vincent, F ;
Abenhaim, J ;
Besse, PA ;
Popovic, RS .
SENSORS AND ACTUATORS A-PHYSICAL, 2002, 97-8 :280-288
[10]   Cancer pathology in the year 2000 [J].
Mountford, CE ;
Doran, S ;
Lean, CL ;
Russell, P .
BIOPHYSICAL CHEMISTRY, 1997, 68 (1-3) :127-135