Reagent-controlled stereoselective iodolactonizations

被引：117
作者：
Haas, J
Piguel, S
Wirth, T
机构：
[1] Univ Wales Coll Cardiff, Dept Chem, Cardiff CF10 3TB, S Glam, Wales
[2] Univ Basel, Inst Organ Chem, CH-4056 Basel, Switzerland
来源：
ORGANIC LETTERS | 2002年 / 4卷 / 02期
关键词：
D O I：
10.1021/ol0171113
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
GRAPHICS Iodocyclizations are important transformations and among stereocontrolled iodocyclizations mostly substrate-controlled versions using a chiral auxiliary have been successfully investigated. This work reports on stereoselective reagent controlled iodolactonizations applying a new method using a combination of ICI and a primary amine leading to the highest selectivities known so far.
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页码：297 / 300
页数：4
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