Small talk: Cell-to-cell communication in bacteria

被引:549
作者
Bassler, BL [1 ]
机构
[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA
关键词
D O I
10.1016/S0092-8674(02)00749-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In a process called quorum sensing, groups of bacteria communicate with one another to coordinate their behavior and function like a multicellular organism. A diverse array of secreted chemical signal molecules and signal detection apparatuses facilitate highly productive intra- and interspecies relationships.
引用
收藏
页码:421 / 424
页数:4
相关论文
共 11 条
[1]   Structural identification of a bacterial quorum-sensing signal containing boron [J].
Chen, X ;
Schauder, S ;
Potier, N ;
Van Dorsselaer, A ;
Pelczer, I ;
Bassler, BL ;
Hughson, FM .
NATURE, 2002, 415 (6871) :545-549
[2]   AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora [J].
Dong, YH ;
Xu, JL ;
Li, XZ ;
Zhang, LH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (07) :3526-3531
[3]   Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase [J].
Dong, YH ;
Wang, LH ;
Xu, JL ;
Zhang, HB ;
Zhang, XF ;
Zhang, LH .
NATURE, 2001, 411 (6839) :813-817
[4]   Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC [J].
Lyon, GJ ;
Mayville, P ;
Muir, TW ;
Novick, RP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (24) :13330-13335
[5]   Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence [J].
Mayville, P ;
Ji, GY ;
Beavis, R ;
Yang, HM ;
Goger, M ;
Novick, RP ;
Muir, TW .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (04) :1218-1223
[6]   Quorum sensing in bacteria [J].
Miller, MB ;
Bassler, BL .
ANNUAL REVIEW OF MICROBIOLOGY, 2001, 55 :165-199
[7]   PHENAZINE ANTIBIOTIC BIOSYNTHESIS IN PSEUDOMONAS-AUREOFACIENS-30-84 IS REGULATED BY PHZR IN RESPONSE TO CELL-DENSITY [J].
PIERSON, LS ;
KEPPENNE, VD ;
WOOD, DW .
JOURNAL OF BACTERIOLOGY, 1994, 176 (13) :3966-3974
[8]   The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule [J].
Schauder, S ;
Shokat, K ;
Surette, MG ;
Bassler, BL .
MOLECULAR MICROBIOLOGY, 2001, 41 (02) :463-476
[9]   Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing [J].
Watson, WT ;
Minogue, TD ;
Val, DL ;
von Bodman, SB ;
Churchill, MEA .
MOLECULAR CELL, 2002, 9 (03) :685-694
[10]  
ZHANG P, 2002, IN PRESS NATURE