Bionanobots for Drug-Delivery

被引：0
|
作者：
Bellini, Reinaldo [1 ]
Pacheco, Marco Aurelio [1 ]
Furtado, Rodrigues [2 ]
DeAlencastro [2 ]
机构：
[1] Pontifical Catholic Univ Rio de Janeiro, PUC RIO, Rio De Janeiro, RJ, Brazil
[2] Univ Fed Rio de Janeiro, BR-21941 Rio De Janeiro, Brazil
来源：
NANOTECHNOLOGY 2012, VOL 2: ELECTRONICS, DEVICES, FABRICATION, MEMS, FLUIDICS AND COMPUTATIONAL | 2012年
关键词：
Drug delivery; molecular modeling; dendrimers; nanotechnology; Tuberculosis;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
In this work we report a simulation of a bionanobots, for treatment of tuberculosis. Across molecular dynamics we simulate dendrimers of three generations with different pH conditions. We describe the specifics of the complexation and encapsulation of rifampicin inside dendrimer. We also developed an algorithm for coupling molecules inside dendrimers in optimal positions. These results were validated across experimental results of our group not showed here.
引用
收藏
页码：685 / 688
页数：4
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