The Vagotomy Alleviates the Anorectic Effect of an Excess Amount of Dietary Leucine on Rats Fed a Low-Protein Diet

被引:2
|
作者
Yoshimura, Ryoji [1 ]
Ho, Yee Yin [2 ]
Mizushige, Takafumi [2 ,3 ]
Ohinata, Kousaku [2 ]
Kanamoto, Ryuhei [2 ]
机构
[1] Kyoto Prefectural Univ, Grad Sch Life & Environm Sci, Lab Mol Nutr, Sakyo Ku, Kyoto 6068522, Japan
[2] Kyoto Univ, Grad Sch Agr, Div Food Sci & Biotechnol, Uji, Kyoto 6110011, Japan
[3] Kyoto Univ, C PIER, Res Unit Physiol Chem, Sakyo Ku, Kyoto 6068501, Japan
基金
日本学术振兴会;
关键词
excess leucine; vagotomy; rat; anorectic effect; low-protein diet; VAGUS NERVE; FOOD-INTAKE; CHOLECYSTOKININ; METABOLISM;
D O I
10.1271/bbb.130150
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
It is well known that large dose of leucine reduces the food intake and causes growth retardation in experimental animals when leucine is given with a low-protein diet. However, the mechanism for the anorectic effect of leucine has not yet been clarified. We demonstrate here that the anorectic effect of leucine was significantly reduced in a vagotomized rat.
引用
收藏
页码:1593 / 1594
页数:2
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