Immunohistochemical results and case report of an incidental finding of uterine polypoid adenomyoma after long-time therapy for metrorrhagia

被引：1

作者：

Szewczuk, Wiktor ^{[1
]}

Szewczuk, Oksana ^{[2
]}

Czajkowski, Krzysztof ^{[2
]}

Grala, Bartlomiej ^{[1
]}

Semczuk, Andrzej ^{[3
]}

机构：

[1] Mil Inst Med, Dept Pathol, Warsaw, Poland

[2] Warsaw Med Univ, Dept Obstet & Gynecol 2, Warsaw, Poland

[3] Lublin Med Univ, Dept Gynecol 2, 8 Jaczewski St, PL-20059 Lublin, Poland

来源：

PATHOLOGY RESEARCH AND PRACTICE | 2020年 / 216卷 / 07期

关键词：

Uterine polypoid adenomyoma; Immunohistochemisty; BAF250a/ARID1A; Arginase; 2; 1LRH-2E1/NR5A2; Nidogen-2; SF-1/NR5A1; UTERUS; CARCINOMA; PATHOLOGY;

D O I：

10.1016/j.prp.2020.152998

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

We present a 25-year-old female woman with a 9-year history of metrorrhagia, in whom a uterine polypoid adenomyoma (UPA) was incidentally detected. Intense nuclear staining in the uterine adenomyoma tissue showed an immunoreaction with BAF250a/ARID1A, Arginase-2 as well as 1LRH-2E1/NR5A2, suggesting a role of these proteins and transcriptional activity of their genes in uterine polypoid adenomyoma development. Neither Nidogen-2 nor SF-1/NR5A1 were expressed in UPA.

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页数：4

相关论文

共 26 条

[1] Pathology of mixed Mullerian tumours [J].

D'Angelo, Emanuela ;

Prat, Jaime .

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY, 2011, 25 (06) :705-718

[2] Cytological Features of Atypical Polypoid Adenomyoma of the Endometrium A Case Report With Literature Review [J].

Ebisu, Yusuke ;

Arimoto, Tomoko ;

Ishida, Mitsuaki ;

Miyasaka, Chika ;

Uemura, Yoshiko ;

Okada, Hidetaka ;

Tsuta, Koji .

DIAGNOSTIC CYTOPATHOLOGY, 2017, 45 (04) :345-349

[3]

Edwards James M, 2012, Gynecol Oncol Case Rep, V2, P29, DOI 10.1016/j.gynor.2011.12.004

[4] Positron emission tomography findings in atypical polypoid adenomyoma [J].

Fukami, Tatsuya ;

Yoshikai, Tomonori ;

Tsujioka, Hiroshi ;

Tohyama, Atsushi ;

Sorano, Sumire ;

Matsuoka, Sakiko ;

Yamamoto, Hiroko ;

Nakamura, Sumie ;

Goto, Maki ;

Matsuoka, Ryoei ;

Oya, Masafumi ;

Torii, Yoshikuni ;

Eguchi, Fuyuki .

RARE TUMORS, 2016, 8 (01) :14-16

[5] ATYPICAL POLYPOID ADENOMYOMAS OF THE UTERUS [J].

FUKUNAGA, M ;

ENDO, Y ;

USHIGOME, S ;

ISHIKAWA, E .

HISTOPATHOLOGY, 1995, 27 (01) :35-42

[6] Adenomyosis of Uterus with Adenomyoma of Fallopian Tube [J].

Ganitha, G. ;

Sivaselvam, S. ;

Chakravarthy, A. R. .

JOURNAL OF OBSTETRICS AND GYNECOLOGY OF INDIA, 2014, 64 (03) :221-223

[7]

Huang C, 2017, GYNECOL MINIM INVASI, V6, P129, DOI 10.1016/j.gmit.2016.08.006

[8] A mixed carcinoma of the uterus arising from an atypical polypoid adenomyoma: a case report [J].

Kato, Y. ;

Kiyomizu, M. ;

Watanabe, A. ;

Takehara, Y. ;

Ogawa, K. ;

Suganuma, I. .

EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2016, 37 (06) :864-866

[9] ENDOMETRIAL CARCINOMA ARISING IN A LARGE POLYPOID ADENOMYOMA OF THE UTERUS [J].

KAY, S ;

FRABLE, WJ ;

GOPLERUD, DR .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 1988, 7 (04) :391-398

[10] Stromal p16 Expression Helps Distinguish Atypical Polypoid Adenomyoma From Myoinvasive Endometrioid Carcinoma of the Uterus [J].

Kihara, Atsushi ;

Amano, Yusuke ;

Yoshimoto, Taichiro ;

Matsubara, Daisuke ;

Fukushima, Noriyoshi ;

Fujiwara, Hiroyuki ;

Niki, Toshiro .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2019, 43 (11) :1526-1535