Kinases and Cancer

被引:120
作者
Cicenas, Jonas [1 ,2 ,3 ]
Zalyte, Egle [2 ]
Bairoch, Amos [4 ,5 ]
Gaudet, Pascale [4 ]
机构
[1] Univ Vienna, Dept Microbiol Immunol & Genet, Max F Perutz Labs, A-1030 Vienna, Austria
[2] Vilnius Univ, Life Sci Ctr, Inst Biochem, Prote Ctr, Sauletekio Al 7, LT-10257 Vilnius, Lithuania
[3] MAP Kinase Resource, Bioinformat, Melchiorstr 9, CH-3027 Bern, Switzerland
[4] SIB, CALIPHO Grp, 1 Rue Michel Servet, CH-1211 Geneva 4, Switzerland
[5] Univ Geneva, Fac Med, 1 Rue Michel Servet, CH-1211 Geneva 4, Switzerland
关键词
CELL LUNG-CANCER; GROWTH-FACTOR RECEPTOR; IN-SITU HYBRIDIZATION; BREAST-CANCER; POOR-PROGNOSIS; GENE AMPLIFICATION; COLORECTAL-CANCER; EPIGENETIC INACTIVATION; PANCREATIC-CANCER; TARGETED THERAPY;
D O I
10.3390/cancers10030063
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页数:7
相关论文
共 64 条
[1]   Role of EGFR as prognostic factor in head and neck cancer patients treated with surgery and postoperative radiotherapy: proposal of a new approach behind the EGFR overexpression [J].
Alterio, Daniela ;
Marvaso, Giulia ;
Maffini, Fausto ;
Gandini, Sara ;
Chiocca, Susanna ;
Ferrari, Annamaria ;
Preda, Lorenzo ;
Rocca, Maria Cossu ;
Lepanto, Daniela ;
Fodor, Cristiana ;
Volpe, Stefania ;
Dicuonzo, Samantha ;
Laudati, Antonio ;
Giugliano, Gioacchino ;
Ansarin, Mohssen ;
Jereczek-Fossa, Barbara A. .
MEDICAL ONCOLOGY, 2017, 34 (06)
[2]   MET Amplification Is Not Rare and Predicts Unfavorable Clinical Outcomes in Patients With Recurrent/Metastatic Gastric Cancer After Chemotherapy [J].
An, Xin ;
Wang, Fang ;
Shao, Qiong ;
Wang, Feng-Hua ;
Wang, Zhi-Qiang ;
Chen, Cui ;
Li, Cong ;
Luo, Hui-Yan ;
Zhang, Dong-Sheng ;
Xu, Rui-Hua ;
Li, Yu-Hong .
CANCER, 2014, 120 (05) :675-682
[3]  
Archewa P, 2017, J INVESTIG CLIN DENT, V8, DOI 10.1111/jicd.12194
[4]   Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion [J].
Chang, Nakho ;
Lee, Hye Won ;
Lim, Joung Eun ;
Jeong, Da Eun ;
Song, Hye Jin ;
Kim, Sudong ;
Nam, Do-Hyun ;
Sung, Hyun Hwan ;
Jeong, Byong Chang ;
Seo, Seong Il ;
Jeon, Seong Soo ;
Lee, Hyun Moo ;
Choi, Han-Yong ;
Jeon, Hwang Gyun .
ONCOTARGET, 2016, 7 (32) :51626-51639
[5]   AKT2, A PUTATIVE ONCOGENE ENCODING A MEMBER OF A SUBFAMILY OF PROTEIN-SERINE THREONINE KINASES, IS AMPLIFIED IN HUMAN OVARIAN CARCINOMAS [J].
CHENG, JQ ;
GODWIN, AK ;
BELLACOSA, A ;
TAGUCHI, T ;
FRANKE, TF ;
HAMILTON, TC ;
TSICHLIS, PN ;
TESTA, JR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (19) :9267-9271
[6]   Expression and amplification of Her2, EGFR and cyclin D1 in breast cancer:: Immunohistochemistry and chromogenic in situ hybridization [J].
Cho, Eun Y. ;
Choi, Yoon-La ;
Han, Jae J. ;
Kim, Kyoung-Mee ;
Oh, Young L. .
PATHOLOGY INTERNATIONAL, 2008, 58 (01) :17-25
[7]   The potential role of Akt phosphorylation in human cancers [J].
Cicenas, J. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2008, 23 (01) :1-9
[8]   Phosphorylation of tyrosine 1248-ERBB2 measured by chemiluminescence-linked immunoassay is an independent predictor of poor prognosis in primary breast cancer patients [J].
Cicenas, J ;
Urban, P ;
Küng, W ;
Vuaroqueaux, V ;
Labuhn, M ;
Wight, E ;
Eppenberger, U ;
Eppenberger-Castori, S .
EUROPEAN JOURNAL OF CANCER, 2006, 42 (05) :636-645
[9]   Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2 [J].
Cicenas, J ;
Urban, P ;
Vuaroqueaux, V ;
Labuhn, M ;
Küng, W ;
Wight, E ;
Mayhew, M ;
Eppenberger, U ;
Eppenberger-Castori, S .
BREAST CANCER RESEARCH, 2005, 7 (04) :R394-R401
[10]  
Cicenas J., 2015, PAGEPress, V4, P31, DOI DOI 10.4081/MK.2015.5700