Cytomegalovirus Retinitis in an ALL Child on Exclusive Chemotherapy Treated Successfully With Intravitreal Ganciclovir Alone

被引：16
作者：
Singh, Ramandeep [1 ]
Singh, Rishiraj [1 ]
Trehan, Amita [2 ]
Jain, Richa [2 ]
Bhalekar, Swapnil [1 ]
机构：
[1] Postgrad Inst Med Educ & Res, Adv Eye Ctr, Chandigarh 160012, India
[2] Postgrad Inst Med Educ & Res, Adv Pediat Ctr, Chandigarh 160012, India
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2013年 / 35卷 / 03期
关键词：
ALL; CMV retinitis; intravitreal ganciclovir;
D O I：
10.1097/MPH.0b013e31827078ad
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A child suffering from acute lymphoblastic leukemia on treatment with exclusive chemotherapy presented with vision-threatening cytomegalovirus (CMV) retinitis in 1 eye. Prompt diagnosis and treatment with 3 weekly doses of 2 mg/0.1mL intravitreal ganciclovir resulted in successful healing of CMV retinitis with restoration of visual acuity. In children with acute lymphoblastic leukemia on exclusive chemotherapy without hematopoietic stem cell transplantation, CMV retinitis has been reported in only 1 case in literature. This child was treated successfully with intravenous ganciclovir. This report highlights the use of successful intravitreal ganciclovir in pediatric age group to avoid side effects of systemic ganciclovir.
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收藏
页码：E118 / E119
页数：2
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