Bone Mineral Density Increases in HIV-Infected Children Treated With Long-term Combination Antiretroviral Therapy

被引：13

作者：

Bunders, Madeleine J. ^{[1
]}

Frinking, Olivier ^{[1
]}

Scherpbier, Henriette J. ^{[1
]}

van Arnhem, Lotus A. ^{[1
]}

van Eck-Smit, Berthe L. ^{[2
]}

Kuijpers, Taco W. ^{[1
]}

Zwinderman, Aeilko H. ^{[3
]}

Reiss, Peter ^{[4
,5
]}

Pajkrt, Dasja ^{[1
]}

机构：

[1] Emma Children Hosp, Dept Paediat Immunol Haematol & Infect Dis, Amsterdam, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Dept Nucl Med, NL-1105 AZ Amsterdam, Netherlands

[3] Univ Amsterdam, Acad Med Ctr, Dept Clin Epidemiol Biostat & Bioinformat, NL-1105 AZ Amsterdam, Netherlands

[4] Univ Amsterdam, Acad Med Ctr, Ctr Infect & Immun, Div Infect Dis, NL-1105 AZ Amsterdam, Netherlands

[5] Univ Amsterdam, Acad Med Ctr, Dept Global Hlth, Amsterdam Inst Global Hlth & Dev, NL-1105 AZ Amsterdam, Netherlands

来源：

CLINICAL INFECTIOUS DISEASES | 2013年 / 56卷 / 04期

关键词：

bone mineral density; pediatric HIV; cART; TENOFOVIR DISOPROXIL FUMARATE; AIDS;

D O I：

10.1093/cid/cis917

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The long-term treatment of human immunodeficiency virus (HIV)-infected children with combination antiretroviral therapy (cART) requires assessment of potential adverse effects, such as osteoporosis. Longitudinal data on bone mineral density (BMD) in HIV-infected children showed that cumulative treatment with cART had a positive impact on BMD over time.

引用

页码：583 / 586

页数：4

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