Bone Mineral Density Increases in HIV-Infected Children Treated With Long-term Combination Antiretroviral Therapy

被引:13
|
作者
Bunders, Madeleine J. [1 ]
Frinking, Olivier [1 ]
Scherpbier, Henriette J. [1 ]
van Arnhem, Lotus A. [1 ]
van Eck-Smit, Berthe L. [2 ]
Kuijpers, Taco W. [1 ]
Zwinderman, Aeilko H. [3 ]
Reiss, Peter [4 ,5 ]
Pajkrt, Dasja [1 ]
机构
[1] Emma Children Hosp, Dept Paediat Immunol Haematol & Infect Dis, Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Dept Nucl Med, NL-1105 AZ Amsterdam, Netherlands
[3] Univ Amsterdam, Acad Med Ctr, Dept Clin Epidemiol Biostat & Bioinformat, NL-1105 AZ Amsterdam, Netherlands
[4] Univ Amsterdam, Acad Med Ctr, Ctr Infect & Immun, Div Infect Dis, NL-1105 AZ Amsterdam, Netherlands
[5] Univ Amsterdam, Acad Med Ctr, Dept Global Hlth, Amsterdam Inst Global Hlth & Dev, NL-1105 AZ Amsterdam, Netherlands
关键词
bone mineral density; pediatric HIV; cART; TENOFOVIR DISOPROXIL FUMARATE; AIDS;
D O I
10.1093/cid/cis917
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The long-term treatment of human immunodeficiency virus (HIV)-infected children with combination antiretroviral therapy (cART) requires assessment of potential adverse effects, such as osteoporosis. Longitudinal data on bone mineral density (BMD) in HIV-infected children showed that cumulative treatment with cART had a positive impact on BMD over time.
引用
收藏
页码:583 / 586
页数:4
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