Cytokine chemokine cascades in immunity to tuberculosis

被引：182

作者：

Orme, IM ^{[1
]}

Cooper, AM ^{[1
]}

机构：

[1] Colorado State Univ, Mycobacteria Res Labs, Dept Microbiol, Ft Collins, CO 80523 USA

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 07期

关键词：

D O I：

10.1016/S0167-5699(98)01438-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The relationship between acquired specific resistance and delayed-type hypersensitivity (DTH) in immunity to tuberculosis has long been a topic of debate. Here, Ian Orme and Andrea Cooper propose that the events are separate mechanisms; protection is cytokine driven and initially controls the infection, whereas DTH is primarily chemokine driven and functions to wall off the infection and prevent further dissemination.

引用

页码：307 / 312

页数：6

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