Cytokine chemokine cascades in immunity to tuberculosis

被引：182
作者：
Orme, IM [1 ]
Cooper, AM [1 ]
机构：
[1] Colorado State Univ, Mycobacteria Res Labs, Dept Microbiol, Ft Collins, CO 80523 USA
来源：
IMMUNOLOGY TODAY | 1999年 / 20卷 / 07期
关键词：
D O I：
10.1016/S0167-5699(98)01438-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The relationship between acquired specific resistance and delayed-type hypersensitivity (DTH) in immunity to tuberculosis has long been a topic of debate. Here, Ian Orme and Andrea Cooper propose that the events are separate mechanisms; protection is cytokine driven and initially controls the infection, whereas DTH is primarily chemokine driven and functions to wall off the infection and prevent further dissemination.
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收藏
页码：307 / 312
页数：6
相关论文
共 57 条
[1]   Host responses and antigens involved in protective immunity to Mycobacterium tuberculosis [J].
Andersen, P .
SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1997, 45 (02) :115-131
[2]  
ANDERSEN P, 1995, J IMMUNOL, V154, P3359
[3]   NATURAL IMMUNITY - A T-CELL-INDEPENDENT PATHWAY OF MACROPHAGE ACTIVATION, DEFINED IN THE SCID MOUSE [J].
BANCROFT, GJ ;
SCHREIBER, RD ;
UNANUE, ER .
IMMUNOLOGICAL REVIEWS, 1991, 124 :5-24
[4]   MOUSE NK1(+) T-CELLS [J].
BENDELAC, A .
CURRENT OPINION IN IMMUNOLOGY, 1995, 7 (03) :367-374
[5]   Mouse CD1-specific NK1 T cells: Development, specificity, and function [J].
Bendelac, A ;
Rivera, MN ;
Park, SH ;
Roark, JH .
ANNUAL REVIEW OF IMMUNOLOGY, 1997, 15 :535-562
[6]   CD1 RECOGNITION BY MOUSE NK1(+) T-LYMPHOCYTES [J].
BENDELAC, A ;
LANTZ, O ;
QUIMBY, ME ;
YEWDELL, JW ;
BENNINK, JR ;
BRUTKIEWICZ, RR .
SCIENCE, 1995, 268 (5212) :863-865
[7]   An innate view of gamma delta T cells [J].
Boismenu, R ;
Havran, WL .
CURRENT OPINION IN IMMUNOLOGY, 1997, 9 (01) :57-63
[8]   THE ROLE OF GAMMA-DELTA LYMPHOCYTES-T IN INFECTION [J].
BORN, WK ;
HARSHAN, K ;
MODLIN, RL ;
OBRIEN, RL .
CURRENT OPINION IN IMMUNOLOGY, 1991, 3 (04) :455-459
[9]   Immunology - T cells and dendritic cells get intimate [J].
Bottomly, K .
SCIENCE, 1999, 283 (5405) :1124-1125
[10]   Role of γδ T cells in immunity to infectious diseases and the regulation of hematalymphoid cell development [J].
Carding, SR .
IMMUNOLOGIC RESEARCH, 1998, 17 (1-2) :13-22
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