Friedel-Crafts Acylation Reactions Using Esters

被引：11

作者：

Chavan, Subhash P. ^{[1
]}

Garai, Sumanta ^{[1
]}

Dutta, Achintya Kumar ^{[2
]}

Pal, Sourav ^{[2
]}

机构：

[1] CSIR NCL Natl Chem Lab, Div Organ Chem, Pune 411008, Maharashtra, India

[2] CSIR NCL Natl Chem Lab, Div Phys Chem, Pune 411008, Maharashtra, India

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 2012卷 / 35期

关键词：

Acylation; C-C coupling; Cyclization; Esters; Synthetic methods; CARBOXYLIC-ACIDS; AROMATIC ETHERS; MELDRUMS ACIDS; SOLID-SURFACE; ALKYLATION; ARENES; CATALYSTS; CHLORIDE; PHENOLS; ANISOLE;

D O I：

10.1002/ejoc.201201181

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intermolecular and intramolecular Friedel-Crafts acylation reactions of various aliphatic and aromatic esters at room temperature with the use of very simple reagents and activating groups in are described. The products were obtained in good yield (60-85%). The detailed mechanistic pathway was studied by DFT calculations and supported by experimental evidence.

引用

页码：6841 / 6845

页数：5

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