Instrumentation and Biological Applications of High-Resolution Frequency Modulation Atomic Force Microscopy in Liquid

被引：1
作者：
Fukuma, Takeshi [1 ,2 ]
机构：
[1] Kanazawa Univ, Frontier Sci Org, Kanazawa, Ishikawa 9201192, Japan
[2] Japan Sci & Technol Agcy, PRESTO, Kawaguchi, Saitama 3320012, Japan
来源：
JOURNAL OF NANO RESEARCH | 2008年 / 4卷
关键词：
Frequency Modulation Atomic Force Microscopy; High-Resolution Imaging; Mica; Biological Membranes; Amyloid Fibrils;
D O I：
10.4028/www.scientific.net/JNanoR.4.1
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Frequency modulation atomic force microscopy (FM-AFM) has been a powerful tool for imaging atomic-scale structures and properties of various materials including metals, semiconductors, metal oxides, alkali halides and organic systems. Whilst the method has been used mainly in ultrahigh vacuum environments, recent progress in FM-AFM instrumentation made it possible to apply this technique also to investigations in liquid. This technological innovation opened up a variety of applications of FM-AFM in biology and electrochemistry. To date, the improved FM-AFM instrument and technique have been applied to investigations of several biological materials, providing novel information that has not been accessible with other imaging techniques. In this review, I will summarize the recent progress in FM-AFM instrumentation and biological applications in liquid.
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页码：1 / 10
页数：10
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