Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore

被引：10

作者：

Tan, Chuen Wen ^{[1
]}

Fan, Bingwen Eugene ^{[2
,3
]}

Teo, Winnie Z. Y. ^{[4
,5
]}

Tung, Moon Ley ^{[4
]}

Shafi, Humaira ^{[6
]}

Christopher, Dheepa ^{[2
,3
]}

Zheng, Shuwei ^{[7
]}

Peh, Wee Ming ^{[7
,8
]}

Chan, Stephrene Seok Wei ^{[2
]}

Chong, Vanessa Cui Lian ^{[2
]}

Gallardo, Christian Aledia ^{[2
]}

Chang, Cheng Chieh Ray ^{[2
]}

Ling, Li Min ^{[9
]}

Tan, Jing Yuan ^{[10
]}

Lee, Ken Cheah Hooi ^{[10
]}

Phua, Ghee Chee ^{[10
]}

Cherng, Benjamin Pei Zhi ^{[11
]}

Low, Jenny Guek Hong ^{[11
,12
]}

Ho, Vui Kian ^{[8
]}

Prasad, Vishnu ^{[3
]}

Wong, Lester Jung Long ^{[13
]}

Lim, Cheryl Xiu Qi ^{[4
]}

Chee, Yen Lin ^{[4
]}

Ong, Kiat Hoe ^{[2
]}

Lee, Lai Heng ^{[1
]}

Ng, Heng Joo ^{[1
]}

Yap, Eng Soo ^{[4
,14
,15
]}

机构：

[1] Singapore Gen Hosp, Dept Haematol, Singapore, Singapore

[2] Tan Tock Seng Hosp, Dept Haematol, Singapore, Singapore

[3] Khoo Teck Puat Hosp, Dept Lab Med, Singapore, Singapore

[4] Natl Univ Canc Inst, Dept Haematoloncol, Singapore, Singapore

[5] Alexandra Hosp, Fast Program, Singapore, Singapore

[6] Changi Gen Hosp, Dept Infect Dis, Singapore, Singapore

[7] Sengkang Gen Hosp, Dept Gen Med, Singapore, Singapore

[8] Sengkang Gen Hosp, Dept Intens Care Med, Singapore, Singapore

[9] Natl Ctr Infect Dis, Dept Infect Dis, Singapore, Singapore

[10] Singapore Gen Hosp, Dept Resp & Crit Care Med, Singapore, Singapore

[11] Singapore Gen Hosp, Dept Infect Dis, Singapore, Singapore

[12] Duke NUS, Programme Emerging Infect Dis, Singapore, Singapore

[13] Khoo Teck Puat Hosp, Div Med, Singapore, Singapore

[14] Ng Teng Fong Gen Hosp, Dept Med, Singapore, Singapore

[15] Natl Univ Singapore Hosp, Dept Lab Med, Singapore, Singapore

来源：

THROMBOSIS JOURNAL | 2021年 / 19卷 / 01期

关键词：

COVID-19; Thrombosis; Critical care;

D O I：

10.1186/s12959-021-00268-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients. Method and results This is a national multicenter retrospective observational study involving all consecutive adult COVID-19 patients who required intensive care units (ICU) admission between 23 January 2020 and 30 April 2020 in Singapore. One hundred eleven patients were included and the venous and arterial thrombotic rates in ICU were 1.8% (n = 2) and 9.9% (n = 11), respectively. Major bleeding rate was 14.8% (n = 16). Conclusions Critically ill COVID-19 patients in Singapore have lower venous thromboembolism but higher arterial thrombosis rates and bleeding manifestations than other reported cohorts.

引用

页数：7

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