Electrocardiographic manifestations of COVID-19

被引:84
作者
Long, Brit [1 ]
Brady, William J. [2 ]
Bridwell, Rachel E. [3 ]
Ramzy, Mark [4 ]
Montrief, Tim [4 ]
Singh, Manpreet [5 ]
Gottlieb, Michael [6 ]
机构
[1] Brooke Army Med Ctr, Res, SAUSHEC, Emergency Med, Ft Sam Houston, TX 78234 USA
[2] Univ Virginia, Sch Med, Dept Emergency Med, Charlottesville, VA 22908 USA
[3] Brooke Army Med Ctr, SAUSHEC, Emergency Med, Ft Sam Houston, TX 78234 USA
[4] Univ Pittsburgh, Med Ctr, Dept Crit Care Med, Pittsburgh, PA USA
[5] Harbor UCLA Med Ctr, Dept Emergency Med, Torrance, CA 90509 USA
[6] Rush Univ, Dept Emergency Med, Med Ctr, Chicago, IL 60612 USA
关键词
COVFD-19; SARS-CoV-2; Coronavirus; Cardiac; ECG; EKG; Electrocardiogram; Emergency medicine; Arrhythmia; Dysrhythmia; CLINICAL CHARACTERISTICS; MYOCARDITIS;
D O I
10.1016/j.ajem.2020.12.060
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Introduction: Coronavirus disease of 2019 (COVID-19) is a lower respiratory tract infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This disease can impact the cardiovascular system and lead to abnormal electrocardiographic (ECG) findings. Emergency clinicians must be aware of the ECG manifestations of COVID-19. Objective: This narrative review outlines the pathophysiology and electrocardiographic findings associated with COVID-19. Discussion: COVID-19 is a potentially critical illness associated with a variety of ECG abnormalities, with up to 90% of critically ill patients demonstrating at least one abnormality. The ECG abnormalities in COVID-19 may be due to cytokine storm, hypoxic injury, electrolyte abnormalities, plaque rupture, coronary spasm, microthrombi, or direct endothelial or myocardial injury. While sinus tachycardia is the most common abnormality, others include supraventricular tachycardias such as atrial fibrillation or flutter, ventricular arrhythmias such as ventricular tachycardia or fibrillation, various bradycardias, interval and axis changes, and ST segment and T wave changes. Several ECG presentations are associated with poor outcome, including atrial fibrillation, QT interval prolongation, ST segment and T wave changes, and ventricular tachycardia/fibrillation. Conclusions: This review summarizes the relevant ECG findings associated with COVID-19. Knowledge of these findings in COVID-19-related electrocardiographic presentations may assist emergency clinicians in the evaluation and management of potentially infected and infected patients. Published by Elsevier Inc.
引用
收藏
页码:96 / 103
页数:8
相关论文
共 78 条
[21]  
DOYEN D, 2020, LANCET, DOI [DOI 10.1016/S0140-6736(20)30912-0, 10.1016/S0140-6736(20)30912-0]
[22]   Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic [J].
Driggin, Elissa ;
Madhavan, Mahesh V. ;
Bikdeli, Behnood ;
Chuich, Taylor ;
Laracy, Justin ;
Biondi-Zoccai, Giuseppe ;
Brown, Tyler S. ;
Nigoghossian, Caroline Der ;
Zidar, David A. ;
Haythe, Jennifer ;
Brodie, Daniel ;
Beckman, Joshua A. ;
Kirtane, Ajay J. ;
Stone, Gregg W. ;
Krumholz, Harlan M. ;
Parikh, Sahil A. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (18) :2352-2371
[23]   Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan A Retrospective Observational Study [J].
Du, Yingzhen ;
Tu, Lei ;
Zhu, Pingjun ;
Mu, Mi ;
Wang, Runsheng ;
Yang, Pengcheng ;
Wang, Xi ;
Hu, Chao ;
Ping, Rongyu ;
Hu, Peng ;
Li, Tianzhi ;
Cao, Feng ;
Chang, Christopher ;
Hu, Qinyong ;
Jin, Yang ;
Xu, Guogang .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 201 (11) :1372-1379
[24]   The Prognostic Value of Electrocardiogram at Presentation to Emergency Department in Patients With COVID-19 [J].
Elias, Pierre ;
Poterucha, Timothy J. ;
Jain, Sneha S. ;
Sayer, Gabriel ;
Raikhelkar, Jayant ;
Fried, Justin ;
Clerkin, Kevin ;
Griffin, Jan ;
DeFilippis, Ersilia M. ;
Gupta, Aakriti ;
Lawlor, Matthew ;
Madhavan, Mahesh ;
Rosenblum, Hannah ;
Roth, Zachary B. ;
Natarajan, Karthik ;
Hripcsak, George ;
Perotte, Adler ;
Wan, Elaine Y. ;
Saluja, Amardeep ;
Dizon, Jose ;
Ehlert, Frederick ;
Morrow, John P. ;
Yarmohammadi, Hirad ;
Kumaraiah, Deepa ;
Redford, Bjorn ;
Gavin, Nicholas ;
Kirtane, Ajay ;
Rabbani, Leroy ;
Burkhoff, Dan ;
Moses, Jeffrey ;
Schwartz, Allan ;
Leon, Martin ;
Uriel, Nir .
MAYO CLINIC PROCEEDINGS, 2020, 95 (10) :2099-2109
[25]   Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic? [J].
Esler, Murray ;
Esler, Danielle .
JOURNAL OF HYPERTENSION, 2020, 38 (05) :781-782
[26]   The Variety of Cardiovascular Presentations of COVID-19 [J].
Fried, Justin A. ;
Ramasubbu, Kumudha ;
Bhatt, Reema ;
Topkara, Veli K. ;
Clerkin, Kevin J. ;
Horn, Evelyn ;
Rabbani, LeRoy ;
Brodie, Daniel ;
Jain, Sneha S. ;
Kirtane, Ajay J. ;
Masoumi, Amirali ;
Takeda, Koji ;
Kumaraiah, Deepa ;
Burkhoff, Daniel ;
Leon, Martin ;
Schwartz, Allan ;
Uriel, Nir ;
Sayer, Gabriel .
CIRCULATION, 2020, 141 (23) :1930-1936
[27]   Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19) [J].
Giudicessi, John R. ;
Noseworthy, Peter A. ;
Friedman, Paul A. ;
Ackerman, Michael J. .
MAYO CLINIC PROCEEDINGS, 2020, 95 (06) :1213-1221
[28]   Clinical Course and Factors Associated With Hospitalization and Critical Illness Among COVID-19 Patients in Chicago, Illinois [J].
Gottlieb, Michael ;
Sansom, Sarah ;
Frankenberger, Casey ;
Ward, Edward ;
Hota, Bala .
ACADEMIC EMERGENCY MEDICINE, 2020, 27 (10) :963-973
[29]   Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) [J].
Guo, Tao ;
Fan, Yongzhen ;
Chen, Ming ;
Wu, Xiaoyan ;
Zhang, Lin ;
He, Tao ;
Wang, Hairong ;
Wan, Jing ;
Wang, Xinghuan ;
Lu, Zhibing .
JAMA CARDIOLOGY, 2020, 5 (07) :811-818
[30]   Value of electrocardiography in coronavirus disease 2019 (COVID-19) [J].
Haseeb, Sohaib ;
Gul, Enes Elvin ;
Cinier, Goksel ;
Bazoukis, George ;
Alvarez-Garcia, Jesus ;
Garcia-Zamora, Sebastian ;
Lee, Sharen ;
Yeung, Cynthia ;
Liu, Tong ;
Tse, Gary ;
Baranchuk, Adrian .
JOURNAL OF ELECTROCARDIOLOGY, 2020, 62 :39-45