Dissection of Mechanisms of Realgar Intervening Telomere Protein POT1, TRF1, TRF2 Expression to Regulate Telomere Dynamics in THP-1 Cells

被引:0
|
作者
Xu, Rui-Rong [1 ]
Song, Nan-Xin [2 ]
Wu, Xiao-Long [2 ]
Cui, Si-Yuan [3 ]
Wang, Zhen-Zhen [3 ]
Wang, Yan [1 ]
Wang, Xin [4 ]
机构
[1] Shandong Univ Tradit Chinese Med, Affiliated Hosp, Dept Hematol, Jinan, Peoples R China
[2] Shandong Univ Tradit Chinese Med, Clin Med Coll 1, Jinan, Shandong, Peoples R China
[3] Shandong Univ Tradit, Affiliated Hosp, Dept Hematol, Jinan, Shandong, Peoples R China
[4] Shandong Prov Hosp, Dept Hematol, Jinan, Shandong, Peoples R China
关键词
D O I
10.1182/blood.V128.22.5896.5896
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
5896
引用
收藏
页数:4
相关论文
共 50 条
  • [41] α-Terpineol Induces Shelterin Components TRF1 and TRF2 to Mitigate Senescence and Telomere Integrity Loss via A Telomerase-Independent Pathway
    Kapetanou, Marianna
    Athanasopoulou, Sophia
    Goutas, Andreas
    Makatsori, Dimitra
    Trachana, Varvara
    Gonos, Efstathios
    ANTIOXIDANTS, 2024, 13 (10)
  • [42] Targeting assay to study the cis functions of human telomeric proteins:: Evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2
    Ancelin, K
    Brunori, M
    Bauwens, S
    Koering, CE
    Brun, C
    Ricoul, M
    Pommier, JP
    Sabatier, L
    Gilson, E
    MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (10) : 3474 - 3487
  • [43] TRF1、TRF2及POT1 mRNA在前列腺癌组织中的表达及临床意义
    王英磊
    张莹莹
    孟琳
    肖琳
    范成娟
    李磊
    张任亚
    赵战魁
    中国老年学杂志, 2016, 36 (21) : 5234 - 5235
  • [44] TRF2-Tethered TIN2 Can Mediate Telomere Protection by TPP1/POT1
    Frescas, David
    de lange, Titia
    MOLECULAR AND CELLULAR BIOLOGY, 2014, 34 (07) : 1349 - 1362
  • [45] TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication
    Nie, Xin
    Xiao, Danqing
    Ge, Yuanlong
    Xie, Yujie
    Zhou, Haoxian
    Zheng, Tian
    Li, Xiaocui
    Liu, Haiying
    Huang, Hui
    Zhao, Yong
    CELL DEATH AND DIFFERENTIATION, 2021, 28 (03): : 1062 - 1075
  • [46] Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 when TPP1 Is Absent
    Janovic, Tomas
    Stojaspal, Martin
    Veverka, Pavel
    Horakova, Denisa
    Hofr, Ctirad
    JOURNAL OF MOLECULAR BIOLOGY, 2019, 431 (17) : 3289 - 3301
  • [47] Severity of coronary artery disease at the late period after low dose radiation exposure is influenced by leukocyte TRF1, TRF2 genes expression and telomere length
    Bazyka, D.
    Ilienko, I.
    Bazyka, O.
    EUROPEAN HEART JOURNAL, 2017, 38 : 833 - 833
  • [48] TRF2 recruits nucleolar protein TCOF1 to coordinate telomere transcription and replication
    Xin Nie
    Danqing Xiao
    Yuanlong Ge
    Yujie Xie
    Haoxian Zhou
    Tian Zheng
    Xiaocui Li
    Haiying Liu
    Hui Huang
    Yong Zhao
    Cell Death & Differentiation, 2021, 28 : 1062 - 1075
  • [49] Different Role of TRF1 and TRF2 Expression in Non-Small Cell Lung Cancers
    Chae, Mincheol
    Lee, Jae-Ho
    Park, Jong Ho
    Keum, Dong Yoon
    Jung, Hanna
    Lee, Youngok
    Lee, Deok Heon
    ONCOTARGETS AND THERAPY, 2024, 17 : 463 - 469
  • [50] Age intrinsic loss of telomere protection via TRF1 reduction in endothelial cells
    Hohensinner, P. J.
    Kaun, C.
    Buchberger, E.
    Ebenbauer, B.
    Demyanets, S.
    Huk, I.
    Eppel, W.
    Maurer, G.
    Huber, K.
    Wojta, J.
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2016, 1863 (02): : 360 - 367