Retinal pigment epithelial tear after intravitreal ranibizumab

被引：60

作者：

Bakri, Sophie J. ^{[1
]}

Kitzmann, Anna S. ^{[1
]}

机构：

[1] Mayo Clin, Coll Med, Dept Ophthalmol, Rochester, MN 55905 USA

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 2007年 / 143卷 / 03期

关键词：

D O I：

10.1016/j.ajo.2006.11.047

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

PURPOSE: To report two cases of a retinal pigment epithelial (RPE) tear after intravitreal injection of 0.05 mg ranibizumab. DESIGN: Observational case report. METHODS: Two patients with choroidal neovascularization (CNV) resulting from age-related macular degeneration (AMD) were treated with an intravitreal injection of ranibizumab. RESULTS: Both patients were found to have a RPE tear on follow-up visits at one month, confirmed by optical coherence tomography (OCT) and by fluorescein or indocyanine green angiography. CONCLUSIONS: RPE tears may occur after intravitreal injection of ranibizumab. Further study is needed to determine whether CNV membranes associated with pigment epithelial detachments (PED) are more likely to develop RPE tears after treatment with anti-vascular endothelial growth factor (anti-VEGF) agents.

引用

页码：505 / 507

页数：3

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