Recent Advances in the Synthesis of Indanes and Indenes

被引:190
作者
Gabriele, Bartolo [1 ]
Mancuso, Raffaella [1 ]
Veltri, Lucia [1 ]
机构
[1] Univ Calabria, Dept Chem & Chem Technol, LISOC, Via Pietro Bucci 12-C, I-87036 Arcavacata Di Rende, CS, Italy
关键词
carbocyclization; indanes; indenes; reaction mechanisms; synthetic methods; ONE-POT SYNTHESIS; FRIEDEL-CRAFTS REACTION; HIGHLY SUBSTITUTED INDENES; CATALYZED DOMINO REACTIONS; CIS-STILBENOID HYDROCARBONS; H BOND ACTIVATION; EFFICIENT SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; STEREOSELECTIVE-SYNTHESIS;
D O I
10.1002/chem.201503933
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Indanes and indenes are among the most important carbocycles. Many indane and indene derivatives have shown important pharmacological activities, and the indane and indene nuclei are structural motifs present in several natural products of biological relevance. In spite of their importance, only a few reviews on their preparation methods have appeared so far in the literature, the most recent ones being published about ten years ago. The present Review is aimed at filling this gap, presenting some of the most important and innovative approaches to indanes and indenes that have been published in the course of the last ten years (coverage: from 2005 to May, 2015).
引用
收藏
页码:5056 / 5094
页数:39
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