Variation of Metabolite and Hormone Contents in Human Milk

被引：41

作者：

Demmelmair, Hans ^{[1
]}

Koletzko, Berthold ^{[1
]}

机构：

[1] Univ Munich, Med Ctr, Dr von Hauner Childrens Hosp, Div Metab & Nutr Med, Lindwurmstr 4, D-80337 Munich, Germany

来源：

CLINICS IN PERINATOLOGY | 2017年 / 44卷 / 01期

关键词：

Metabolite; Amino acid; Leptin; Insulin; Body mass index; Human milk; HUMAN BREAST-MILK; INFANT FORMULA; BODY-COMPOSITION; PRETERM HUMAN; AMINO-ACID; MACRONUTRIENT COMPOSITION; LEPTIN CONCENTRATIONS; PROTEIN RESTRICTION; POTENTIAL ROLE; WEIGHT-GAIN;

D O I：

10.1016/j.clp.2016.11.007

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Animal studies show that the lactation period contributes to metabolic programming of the offspring and that oral leptin and insulin show bioactivity. Stage of lactation, duration of gestation, maternal body composition, and maternal diet seem to influence the concentrations of small molecules in human milk. Variability of small molecule concentrations seems higher in pre term milk than in term milk. Insulin in human milk shows concentrations similar to plasma. Leptin concentration is lower in milk than in plasma and reflects maternal body mass index. Early in lactation, leptin could contribute to mediating the association between maternal and infant body composition.

引用

页码：151 / +

页数：15

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