Topoisomerase II as a target for anticancer drugs: When enzymes stop being nice

被引：318
作者：
Fortune, JM
Osheroff, N
机构：
[1] Vanderbilt Univ, Sch Med, Dept Biochem, Nashville, TN 37232 USA
[2] Vanderbilt Univ, Sch Med, Dept Med Hematol Oncol, Nashville, TN 37232 USA
来源：
PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 64 | 2000年 / 64卷
关键词：
D O I：
10.1016/S0079-6603(00)64006-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：221 / 253
页数：33
相关论文
共 273 条
[11]   EXPRESSION, DOMAIN-STRUCTURE, AND ENZYMATIC-PROPERTIES OF AN ACTIVE RECOMBINANT HUMAN DNA TOPOISOMERASE II-BETA [J].
AUSTIN, CA ;
MARSH, KL ;
WASSERMAN, RA ;
WILLMORE, E ;
SAYER, PJ ;
WANG, JC ;
FISHER, LM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (26) :15739-15746
[12]   NOVEL HELA TOPOISOMERASE-II IS THE II-BETA ISOFORM - COMPLETE CODING SEQUENCE AND HOMOLOGY WITH OTHER TYPE-II TOPOISOMERASES [J].
AUSTIN, CA ;
SNG, JH ;
PATEL, S ;
FISHER, LM .
BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1172 (03) :283-291
[13]  
Austin CA, 1998, BIOESSAYS, V20, P215, DOI 10.1002/(SICI)1521-1878(199803)20:3<215::AID-BIES5>3.0.CO
[14]  
2-Q
[15]   Mutagenic properties of topoisomerase-targeted drugs [J].
Baguley, BC ;
Ferguson, LR .
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1998, 1400 (1-3) :213-222
[16]  
Bauman ME, 1997, MODERN PATHOL, V10, P168
[17]  
Beck W T, 1994, Adv Pharmacol, V29B, P145
[18]  
BECK WT, 1993, ADV ENZYME REGUL, V33, P113
[19]   Structure and mechanism of DNA topoisomerase II [J].
Berger, JM ;
Gamblin, SJ ;
Harrison, SC ;
Wang, JC .
NATURE, 1996, 379 (6562) :225-232
[20]   Structure of DNA topoisomerases [J].
Berger, JM .
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1998, 1400 (1-3) :3-18
12345678910