Heat Shock Protein 70 Cytosolic Sequestration by Excess of Free Alpha-Globin Chains Is a Key Mechanism of the Ineffective Erythropoiesis in β-Thalassemia Major Patients

被引：1

作者：

Arlet, Jean-Benoit ^{[1
]}

Ribeil, Jean-Antoine

Hazoume, Adonis ^{[2
]}

Demarest, Samuel ^{[3
]}

Tchertanov, Luba ^{[3
]}

Michael, Dussiot ^{[4
]}

Moura, Ivan Cruz ^{[5
]}

Maciel, Thiago ^{[5
]}

Auclair, Christian

Negre, Olivier ^{[6
]}

Leboulch, Philippe ^{[7
]}

Baudin-creuza, Veronique ^{[8
]}

Garrido, Carmen ^{[2
]}

Courtois, Genevieve ^{[9
]}

Hermine, Olivier ^{[10
]}

机构：

[1] Hop Europeen Georges Pompidou, Serv Med Interne, Paris, France

[2] INSERM, UMR866, Dijon, France

[3] ENS, CNRS, Cachan, France

[4] CNRS, UMR8147, F-75015 Paris, France

[5] Hop Bichat Claude Bernard, INSERM, U699, F-75877 Paris, France

[6] Inst Emerging Dis & Innovat Therapies, INSERM, U962, CEA, Fontenay Aux Roses, France

[7] Harvard Univ, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USA

[8] INSERM, U779, F-94275 Le Kremlin Bicetre, France

[9] Univ Paris 05, CNRS, UMR8147, Hop Necker, F-75270 Paris, France

[10] Hop Necker Enfants Malad, Dept Hematol, Paris, France

来源：

关键词：

D O I：

10.1182/blood.V120.21.823.823

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

823

引用

页数：2