Pharmacophore Modelling Used in Rational Drug Design

被引：0

作者：

Koscova, P. ^{[1
]}

Provaznik, I. ^{[1
]}

机构：

[1] Brno Univ Technol, Fac Elect Engn & Commun, Dept Biomed Engn, Tech 12, Brno 61600, Czech Republic

来源：

CHEMICKE LISTY | 2016年 / 110卷 / 08期

关键词：

drug discovery; rational drug design; pharmacophore; DISCOVERY;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Development of information technologies in recent decades has facilitated also a great progress in the development of new drugs. Methods of Computer-Aided Drug Design allow us to explore the spatial interaction between the receptor and a potential drug. The review deals with a brief summary of these computational methods and is mainly focused on pharmacophore modelling, one of the modern approaches in drug design that has proved to be a useful tool.

引用

页码：575 / 580

页数：6

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