Endoscopic swept-source optical coherence tomography based on a two-axis microelectromechanical system mirror

被引:41
作者
Wang, Donglin [1 ,2 ]
Fu, Linlai [2 ]
Wang, Xin [3 ]
Gong, Zhongjian [3 ]
Samuelson, Sean [4 ]
Duan, Can [4 ]
Jia, Hongzhi [1 ]
Ma, Jun Shan [1 ]
Xie, Huikai
机构
[1] Shanghai Univ Sci & Technol, Minist Educ, Shanghai Key Lab Modern Opt Syst, Engn Res Ctr Opt Instrument & Syst, Shanghai 200093, Peoples R China
[2] WiO Technol Ltd Co, Wuxi 214028, Jiangsu, Peoples R China
[3] Nanjing Med Univ, Wuxi Peoples Hosp, Wuxi 214023, Jiangsu, Peoples R China
[4] Univ Florida, Dept Elect & Comp Engn, Gainesville, FL 32611 USA
基金
美国国家科学基金会;
关键词
optical coherence tomography; microelectromechanical system mirror; oral cancer; MEMS SCANNING CATHETER; IN-VIVO;
D O I
10.1117/1.JBO.18.8.086005
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A microelectromechanical system (MEMS) mirror based endoscopic swept-source optical coherence tomography (SS-OCT) system that can perform three-dimensional (3-D) imaging at high speed is reported. The key component enabling 3-D endoscopic imaging is a two-axis MEMS scanning mirror which has a 0.8 x 0.8 mm(2) mirror plate and a 1.6 x 1.4 mm2 device footprint. The diameter of the endoscopic probe is only 3.5 mm. The imaging rate of the SS-OCT system is 50 frames/s. OCT images of both human suspicious oral leukoplakia tissue and normal buccal mucosa were taken in vivo and compared. The OCT imaging result agrees well with the histopathological analysis. (C) 2013 Society of Photo-Optical Instrumentation Engineers (SPIE)
引用
收藏
页数:5
相关论文
共 22 条
  • [1] Two-axis MEMS scanning catheter for ultrahigh resolution three-dimensional and en face imaging
    Aguirre, Aaron D.
    Herz, Paul R.
    Chen, Yu
    Fujimoto, James G.
    Piyawattanametha, Wibool
    Fan, Li
    Wu, Ming C.
    [J]. OPTICS EXPRESS, 2007, 15 (05): : 2445 - 2453
  • [2] [Anonymous], Z13612000 ANSI LAS I
  • [3] Resonant micro-mirror excited by a thin-film piezoelectric actuator for fast optical beam scanning
    Filhol, F
    Defaÿ, E
    Divoux, C
    Zinck, C
    Delaye, MT
    [J]. SENSORS AND ACTUATORS A-PHYSICAL, 2005, 123-24 : 483 - 489
  • [4] OPTICAL COHERENCE TOMOGRAPHY
    HUANG, D
    SWANSON, EA
    LIN, CP
    SCHUMAN, JS
    STINSON, WG
    CHANG, W
    HEE, MR
    FLOTTE, T
    GREGORY, K
    PULIAFITO, CA
    FUJIMOTO, JG
    [J]. SCIENCE, 1991, 254 (5035) : 1178 - 1181
  • [5] Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror
    Jung, W
    McCormick, DT
    Zhang, J
    Wang, L
    Tien, NC
    Chen, ZP
    [J]. APPLIED PHYSICS LETTERS, 2006, 88 (16)
  • [6] Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography
    Kim, Ki Hean
    Park, B. Hyle
    Maguluri, Gopi N.
    Lee, Tom W.
    Rogomentich, Fran J.
    Bancu, Mirela G.
    Bouma, Brett E.
    de Boer, Johannes F.
    Bernstein, Jonathan J.
    [J]. OPTICS EXPRESS, 2007, 15 (26): : 18130 - 18140
  • [7] Semi-resonant operation of a fiber-cantilever piezotube scanner for stable optical coherence tomography endoscope imaging
    Moon, Sucbei
    Lee, Sang-Won
    Rubinstein, Marc
    Wong, Brian J. F.
    Chen, Zhongping
    [J]. OPTICS EXPRESS, 2010, 18 (20): : 21183 - 21197
  • [8] Endoscopic optical coherence tomography based on a microelectromechanical mirror
    Pan, YT
    Xie, HK
    Fedder, GK
    [J]. OPTICS LETTERS, 2001, 26 (24) : 1966 - 1968
  • [9] Forward imaging OCT endoscopic catheter based on MEMS lens scanning
    Park, Hyeon-Cheol
    Song, Cheol
    Kang, Minseok
    Jeong, Yong
    Jeong, Ki-Hun
    [J]. OPTICS LETTERS, 2012, 37 (13) : 2673 - 2675
  • [10] A 2.8-mm Imaging Probe Based On a High-Fill-Factor MEMS Mirror and Wire-Bonding-Free Packaging for Endoscopic Optical Coherence Tomography
    Samuelson, Sean R.
    Wu, Lei
    Sun, Jingjing
    Choe, Se-woon
    Sorg, Brian S.
    Xie, Huikai
    [J]. JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 2012, 21 (06) : 1291 - 1302