Synthesis, Characterisation and DFT Studies of Stigmasterol Mediated Silver Nanoparticles and Their Anticancer Activity

被引：19

作者：

Kanagamani, K. ^{[1
,2
]}

Muthukrishnan, P. ^{[2
]}

Ilayaraja, M. ^{[3
]}

Shankar, K. ^{[2
]}

Kathiresan, A. ^{[2
]}

机构：

[1] SNS Coll Technol, Dept Chem, Coimbatore 641035, Tamil Nadu, India

[2] Karpagam Univ, Karpagam Acad Higher Educ, Dept Chem, Fac Engn, Coimbatore 641021, Tamil Nadu, India

[3] Arumugam Pillai Seethai Ammal Coll, Dept Chem, Tirupattur 630211, India

来源：

JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS | 2018年 / 28卷 / 03期

关键词：

Silver nanoparticles; Ficus Hispida; DFT studies; Cytotoxicity activity; LEAF EXTRACT; ANTIBACTERIAL ACTIVITY; GREEN SYNTHESIS; CANCER CELLS; BIOSYNTHESIS; CORROSION; EFFICACY; OIL; AG;

D O I：

10.1007/s10904-017-0721-7

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The present investigation reports the facile, reproducible and eco-friendly biological synthesis of nano silver using Ficus Hispida leaf extract (FHLE) as a reductant. The properties of the synthesized silver nanoparticles (Ag-NP's) is characterized by scanning electron microscopy, energy dispersive X-ray spectroscopy, transmission electron microscopy (TEM), UV-visible spectroscopy, Fourier transform infrared spectroscopy and X-ray diffraction studies. The synthesized Ag-NPs are found to have spherical shape with average particle size in the range of 50-100 nm. The XRD studies and selected area electron diffraction pattern of TEM images confirm the face cantered cubic structure of biosynthesised silver nanoparticles. The DFT studies reveal that the stigmasterol present in FHLE is responsible for leaf extract to behave as a reducing agent for reduction of Ag+ ions into Ag-0. The antitumor studies against DLA cell lines of the biosynthesized Ag-NPs is found to have 100% inhibition with concentration of 200 A mu g/ml of Ag-NP's.

引用

页码：702 / 710

页数：9

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