Fertility/longevity trade-offs under limiting-male conditions in mating populations of Caenorhabditis elegans

被引：10

作者：

Wu, Deqing ^{[1
]}

Tedesco, Patricia M. ^{[1
]}

Phillips, Patrick C. ^{[2
]}

Johnson, Thomas E. ^{[1
,3
]}

机构：

[1] Univ Colorado, Inst Behav Genet, Boulder, CO 80309 USA

[2] Univ Oregon, Inst Ecol & Evolut, Eugene, OR 97403 USA

[3] Univ Colorado, Dept Integrat Physiol, Boulder, CO 80309 USA

来源：

EXPERIMENTAL GERONTOLOGY | 2012年 / 47卷 / 10期

关键词：

Genetics; Nematodes; Fertility; Demography; Longevity; Evolutionary theory; Antagonistic pleiotropy; LIFE-SPAN; FITNESS COST; LONGEVITY; NEMATODE; PLEIOTROPY; EVOLUTION; MUTATION; MUTANTS;

D O I：

10.1016/j.exger.2012.06.010

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Evolutionary theories of aging suggest that trade-offs between longevity and fitness should be found under certain conditions. In C. elegans, there is little evidence for the existence of such trade-offs. We asked if fertility/longevity trade-offs exist in populations of randomly mating males and hermaphrodites. We set up a large population of young males and 5-day-old hermaphrodites that were no longer self-fertile. We then allowed themto mate for one day with an equal number young males and then separated hermaphrodites to individual plates and determined daily fertility of individual hermaphrodites. There was a significant negative relationship between late-life fertility and individual longevity. (c) 2012 Elsevier Inc. All rights reserved.

引用

页码：759 / 763

页数：5

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