Tsukamurella: a cause of catheter-related bloodstream infections

被引:35
作者
Bouza, E. [1 ,2 ,3 ]
Perez-Parra, A. [1 ,3 ]
Rosal, M. [1 ,3 ]
Martin-Rabadan, P. [1 ,3 ]
Rodriguez-Creixems, M. [1 ,3 ]
Marin, M. [1 ,3 ]
机构
[1] Univ Gregorio Maranon, Dept Clin Microbiol, Madrid 28007, Spain
[2] REIPI, Madrid 20082010, Spain
[3] Univ Gregorio Maranon, Gen Hosp, Infect Dis Serv, Madrid 28007, Spain
关键词
GORDONA-AURANTIACA RHODOCOCCUS; RAPID IDENTIFICATION; PAUROMETABOLUM; PATIENT; BACTEREMIA;
D O I
10.1007/s10096-008-0607-2
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Tsukamurellae are strictly aerobic Gram-positive rods that can be easily misidentified as Corynebacterium species, Rhodococcus species, Nocardia species, Mycobacterium species, or other Gram-positive aerobic rods. They have been uncommonly reported as a cause of different human infections, including bloodstream infections. We describe 2 new cases of catheter-related bloodstream infections (CR-BSI) caused by Tsukamurella species and review 12 similar cases reported in the literature. Conventional procedures have often misidentified Tsukamurella species as other aerobic Gram-positive rods. This misidentification could be avoided using genotyping. All cases ultimately required the withdrawal of the infected line. The literature provides no firm conclusions regarding ideal choice or duration of antimicrobial therapy for this infection. Tsukamurella species should be added to the list of agents able to produce CR-BSI. Genotypic methods such as PCR 16S rRNA can allow a reliable identification at the genus level of Tsukamurella strains faster than a combination of conventional phenotypic methods.
引用
收藏
页码:203 / 210
页数:8
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